Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | LIG1 | P18858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.37 |
| ▸ | GGT1 | P19440 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3113786 | 0.91 | HPGD (0.45) | ELANECYP3A4KDM4ELIG1HSD17B10 | |
| SCHEMBL4499103 | 0.89 | ELANE (0.53) | ELANECYP3A4KDM4EHSD17B10HPGD | |
| SCHEMBL32687438 | 0.86 | KDM4E (0.56) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL4209791 | 0.86 | KDM4E (0.56) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL8608640 | 0.84 | CYP3A4 (0.43) | CYP3A4KDM4ELIG1HSD17B10HPGD | |
| SCHEMBL28191444 | 0.84 | KDM4E (0.58) | CYP3A4KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL16710282 | 0.84 | LMNA (0.51) | CYP3A4KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL9751711 | 0.84 | ALDH1A1 (0.44) | ELANECYP3A4KDM4ELIG1HSD17B10 | |
| SCHEMBL2987534 | 0.82 | CYP3A4 (0.42) | CYP3A4KDM4ELIG1HSD17B10HPGD | |
| SCHEMBL3961140 | 0.78 | KDM4E (0.45) | CYP3A4KDM4ELIG1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732645-B2 | Aromatic vinyl ether compounds | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2010-06-08 | — | — | US | disclosed |
| EP-2161248-A1 | Aromatic vinyl ether compounds | Daicel Chemical Industries, Ltd. (JP) | 2010-03-10 | — | — | EP | disclosed |
| US-7518021-B2 | Aromatic vinyl ether compounds | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2009-04-14 | — | — | US | disclosed |
| US-20090088592-A1 | AROMATIC VINYL ETHER COMPOUNDS | IWAHAMA TAKAHIRO | 2009-04-02 | — | — | US | disclosed |
| US-20040181098-A1 | Aromatic vinyl ether compounds | EMORY UNIVERSITY | 2004-09-16 | — | — | US | disclosed |
| EP-1413568-A2 | Aromatic vinyl ether compounds | Daicel Chemical Industries, Ltd. (JP) | 2004-04-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040181098-A1 | Aromatic vinyl ether compounds | SUV39H2, SUV39H1, RAVER1 | ELANE 2856/4885CYP3A4 899/4885KDM4E 87/4885 |
| US-20090088592-A1 | AROMATIC VINYL ETHER COMPOUNDS | SUV39H2, SUV39H1, RAVER1 | ELANE 2854/4885CYP3A4 934/4885KDM4E 76/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.