Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.50 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL597702 | 0.92 | MEN1 (0.63) | KMT2AMEN1MAOBMRGPRX4NR4A2 | |
| SCHEMBL29196805 | 0.89 | MEN1 (0.67) | KMT2AMEN1MAOBLMNANR4A2 | |
| SCHEMBL31643552 | 0.87 | HPGD (0.61) | KMT2AMEN1MAOBMRGPRX4CYP3A4 | |
| SCHEMBL1842000 | 0.87 | MEN1 (0.56) | KMT2AMEN1MAOBMRGPRX4NR4A2 | |
| SCHEMBL4499664 | 0.87 | MEN1 (0.56) | KMT2AMEN1MAOBMRGPRX4NR4A2 | |
| SCHEMBL1390623 | 0.86 | CYP3A4 (0.63) | KMT2AMEN1MAOBCYP3A4ALDH1A1 | |
| SCHEMBL8063539 | 0.85 | CYP3A4 (0.53) | KMT2AMEN1CYP3A4ACHEALDH1A1 | |
| SCHEMBL22490923 | 0.84 | MEN1 (0.54) | KMT2AMEN1MAOBMRGPRX4HPGD | |
| SCHEMBL8057855 | 0.83 | MEN1 (0.55) | KMT2AMEN1MAOBMRGPRX4ALDH1A1 | |
| SCHEMBL31643371 | 0.83 | MEN1 (0.52) | KMT2AMEN1MAOBMRGPRX4NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010050445-A1 | BICYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2010-05-06 | — | — | WO | disclosed |