Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29130316 | 0.98 | LMNA (0.38) | LMNA | |
| SCHEMBL27035528 | 0.98 | LMNA (0.38) | LMNA | |
| SCHEMBL2828097 | 0.92 | LMNA (0.37) | LMNA | |
| SCHEMBL28543858 | 0.90 | DNM1 (0.35) | — | |
| SCHEMBL17387531 | 0.89 | LMNA (0.35) | LMNA | |
| SCHEMBL18730166 | 0.89 | LMNA (0.35) | LMNA | |
| Ammonia Solution, Strong SCHEMBL27896209 | 0.88 | DNM1 (0.33) | — | |
| SCHEMBL7778011 | 0.88 | LMNA (0.37) | LMNA | |
| SCHEMBL28541903 | 0.88 | LMNA (0.44) | LMNA | |
| SCHEMBL207406 | 0.86 | LMNA (0.34) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663657-B2 | Moisture curable organopolysiloxane compositions | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2017-05-30 | — | — | US | claimed |
| US-9493691-B2 | Moisture curable organopolysiloxane compositions | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2016-11-15 | — | — | US | claimed |
| US-20160060494-A1 | MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITIONS | MOMENTIVE PERFORMANCE MATERIALS INC. | 2016-03-03 | — | — | US | claimed |
| US-20140350175-A1 | MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITIONS | MOMENTIVE PERFORMANCE MATERIALS INC. | 2014-11-27 | — | — | US | claimed |
| EP-2791198-A1 | MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITIONS | Momentive Performance Materials Inc. (US) | 2014-10-22 | — | — | EP | claimed |
| WO-2013090127-A1 | MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITIONS | MOMENTIVE PERFORMANCE MATERIALS, INC. (US) | 2013-06-20 | — | — | WO | claimed |
| US-20230083453-A1 | NON-SAG COMPOSITION | MOMENTIVE PERFORMANCE MATERIALS INC. | 2023-03-16 | — | — | US | disclosed |
| US-20230060699-A1 | SECONDARY BATTERY PACK WITH IMPROVED THERMAL MANAGEMENT | Elkem Silicones USA Corp. | 2023-03-02 | — | — | US | disclosed |
| EP-3262128-B1 | CURABLE SILOXANE COMPOSITIONS | MOMENTIVE PERFORMANCE MAT INC (US) | 2018-11-21 | — | — | EP | disclosed |
| US-10023699-B2 | Curable siloxane compositions | MOMENTIVE PERFORMANCE MATERIALS, INC. (US) | 2018-07-17 | — | — | US | disclosed |
| EP-2614107-B1 | MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION | MOMENTIVE PERFORMANCE MAT INC (US) | 2018-02-21 | — | — | EP | disclosed |
| US-20180002492-A1 | CURABLE SILOXANE COMPOSITIONS | MOMENTIVE PERFORMANCE MATERIALS INC. | 2018-01-04 | — | — | US | disclosed |
| US-9771459-B2 | Curable siloxane compositions | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2017-09-26 | — | — | US | disclosed |
| EP-2791198-A1 | MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITIONS | Momentive Performance Materials Inc. (US) | 2014-10-22 | — | — | EP | disclosed |
| EP-2776162-A1 | MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION | Momentive Performance Materials Inc. (US) | 2014-09-17 | — | — | EP | disclosed |
| WO-2013101751-A1 | MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION | MOMENTIVE PERFORMANCE MATERIALS, INC. (US) | 2013-07-04 | — | — | WO | disclosed |
| WO-2013090127-A1 | MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITIONS | MOMENTIVE PERFORMANCE MATERIALS, INC. (US) | 2013-06-20 | — | — | WO | disclosed |
| WO-2013090132-A2 | MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITIONS | MOMENTIVE PERFORMANCE MATERIALS, INC. (US) | 2013-06-20 | — | — | WO | disclosed |
| WO-2013071078-A1 | MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION | MOMENTIVE PERFORMANCE MATERIALS, INC. (US) | 2013-05-16 | — | — | WO | disclosed |
| US-20120065308-A1 | MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION | MOMENTIVE PERFORMANCE MATERIALS INC. | 2012-03-15 | — | — | US | disclosed |