Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 15/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 15/20 | 0.49 |
| ▸ | MAPT | P10636 | 12/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.49 |
| ▸ | RAB9A | P51151 | 8/20 | 0.49 |
| ▸ | NPC1 | O15118 | 7/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.49 |
| ▸ | THRB | P10828 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 4/20 | 0.48 |
| ▸ | CRHBP | P24387 | 2/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.48 |
| ▸ | IDE | P14735 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | BLM | P54132 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2057351 | 1.00 | MEN1 (0.49) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL2057354 | 1.00 | MEN1 (0.49) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL2057356 | 1.00 | MEN1 (0.49) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL3196262 | 0.83 | MMP13 (0.42) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL3196246 | 0.83 | MMP13 (0.42) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL4503906 | 0.82 | KDM4E (0.52) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL4503913 | 0.82 | KDM4E (0.52) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL2057371 | 0.80 | MEN1 (0.36) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL2057377 | 0.80 | MEN1 (0.36) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL10036069 | 0.78 | MEN1 (0.54) | MEN1KMT2AMAPTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592188-B2 | environmentally sensitive fluorescent dye covalently linked to a binding domain which has specific affinity for a target molecule; fluorescence resonance energy transfer; detecting changes in the binding, conformational change; detecting human immunodeficiency virus | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-09-22 | — | — | US | disclosed |
| US-20060029946-A1 | Live cell biosensors | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-02-09 | — | — | US | disclosed |