Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 11/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.42 |
| ▸ | MAPT | P10636 | 11/20 | 0.42 |
| ▸ | POLB | P06746 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.40 |
| ▸ | CASP1 | P29466 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3196246 | 1.00 | MMP13 (0.42) | MMP13MEN1KMT2AMAPTPOLB | |
| SCHEMBL4503910 | 0.90 | MMP13 (0.42) | MMP13MEN1KMT2AMAPTPOLB | |
| SCHEMBL4503906 | 0.90 | KDM4E (0.52) | MMP13MEN1KMT2AMAPTPOLB | |
| SCHEMBL4503913 | 0.90 | KDM4E (0.52) | MMP13MEN1KMT2AMAPTPOLB | |
| SCHEMBL13292509 | 0.84 | MEN1 (0.39) | MMP13MEN1KMT2AMAPTPOLB | |
| SCHEMBL13483760 | 0.84 | MEN1 (0.40) | MMP13MEN1KMT2AMAPTPOLB | |
| SCHEMBL4500369 | 0.83 | MEN1 (0.49) | MEN1KMT2AMAPTPOLBHPGD | |
| SCHEMBL2057356 | 0.83 | MEN1 (0.49) | MEN1KMT2AMAPTPOLBHPGD | |
| SCHEMBL2057354 | 0.83 | MEN1 (0.49) | MEN1KMT2AMAPTPOLBHPGD | |
| SCHEMBL2057351 | 0.83 | MEN1 (0.49) | MEN1KMT2AMAPTPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745377-B2 | Labeled peptides, proteins and antibodies and processes and intermediates useful for their preparation | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-06-29 | — | — | US | disclosed |
| US-7662644-B2 | Use of specified fluorescent dyes to conjugate to antibody; detecting binding of an antibody to an antigen; antibody conjugate | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-02-16 | — | — | US | disclosed |
| US-20070218502-A1 | LABELED PEPTIDES, PROTEINS AND ANTIBODIES AND PROCESSES AND INTERMEDIATES USEFUL FOR THEIR PREPARATION | THE SCRIPPS RESEARCH INSTITUTE | 2007-09-20 | — | — | US | disclosed |
| US-7176037-B2 | Labeled peptides, proteins and antibodies and processes and intermediates useful for their preparation | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-02-13 | — | — | US | disclosed |
| US-20050287518-A1 | Labeled peptides, proteins and antibodies and processes and intermediates useful for their preparation | THE SCRIPPS RESEARCH INSTITUTE | 2005-12-29 | — | — | US | disclosed |
| US-6951947-B2 | Labeled peptides, proteins and antibodies and processes and intermediates useful for their preparation | THE SCRIPPS RESEARCH INSTITUTE (US) | 2005-10-04 | — | — | US | disclosed |
| US-20040067537-A1 | Labeled peptides, proteins and antibodies and processes and intermediates useful for their preparation | HAHN KLAUS M (US) | 2004-04-08 | — | — | US | disclosed |
| US-20020055133-A1 | Labeled peptides, proteins and antibodies and processes and intermediates useful for their preparation | SCRIPPS RESEARCH INSTITUTE, THE | 2002-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020055133-A1 | Labeled peptides, proteins and antibodies and processes and intermediates useful for their preparation | ARHGEF1, RHOC, CIT | MMP13 3420/4885MEN1 1305/4885KMT2A 4697/4885 |
| US-20040067537-A1 | Labeled peptides, proteins and antibodies and processes and intermediates useful for their preparation | CIT, RHOC, ARHGEF1 | MMP13 3456/4885MEN1 1276/4885KMT2A 4693/4885 |
| US-20070218502-A1 | LABELED PEPTIDES, PROTEINS AND ANTIBODIES AND PROCESSES AND INTERMEDIATES USEFUL FOR THEIR PREPARATION | CIT, RHOC, ARHGEF1 | MMP13 3456/4885MEN1 1276/4885KMT2A 4693/4885 |
| US-20050287518-A1 | Labeled peptides, proteins and antibodies and processes and intermediates useful for their preparation | ARHGEF1, RHOC, CIT | MMP13 3420/4885MEN1 1305/4885KMT2A 4697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.