SCHEMBL4500417

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4525507	0.90	HSD11B1 (0.42)	HSD11B1HRH3NPC1RAB9AS1PR1
	SCHEMBL4500220	0.90	MRGPRX4 (0.53)	HSD11B1NPC1RAB9ACYP2C9ADRA1A
	SCHEMBL4504216	0.90	HSD11B1 (0.47)	HSD11B1HRH3S1PR1PRKXACVR1
	SCHEMBL4519338	0.90	HSD11B1 (0.60)	HSD11B1HRH3S1PR1PRKXACVR1
	SCHEMBL4514405	0.89	S1PR1 (0.39)	HRH3RXRARXRBRXRGNPC1
	SCHEMBL4519067	0.86	HSD11B1 (0.50)	HSD11B1HRH1FFAR1
	SCHEMBL2988650	0.84	HSD11B1 (0.50)	HSD11B1HRH3CYP2C9CCR5
	SCHEMBL4511746	0.83	MRGPRX4 (0.46)	HSD11B1NPC1RAB9ACYP2C9ADRA1A
	SCHEMBL2993016	0.83	HSD11B1 (0.49)	HSD11B1HRH3CYP2C9CCR5
	SCHEMBL3744013	0.82	HSD11B1 (0.42)	HSD11B1HRH3RXRARXRBRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.