Biguanide

Biguanide

SCHEMBL45009

C1CCCCC1.N=C(N)NC(=N)N

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.38
NOS2 P35228 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biguanide SCHEMBL740584 0.96 F2 (0.36) F2NOS2
Biguanide SCHEMBL9536674 0.96 F2 (0.36) F2NOS2
Biguanide SCHEMBL10825778 0.96 F2 (0.36) F2NOS2
Biguanide SCHEMBL15608913 0.93 F2 (0.35) F2NOS2
Biguanide SCHEMBL8039 0.88
Biguanide SCHEMBL18255803 0.88 MAPK1 (0.31) NOS2
Biguanide SCHEMBL10881314 0.84
Biguanide SCHEMBL5489883 0.84
Biguanide SCHEMBL4217126 0.84
Biguanide SCHEMBL675101 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3930 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240218291-A1 CONTACT LENS TREATING SOLUTION JPMORGAN CHASE BANK, N.A., AS SUCCESSOR AGENT 2024-07-04 US claimed
WO-2024132271-A1 CONTACT LENS TREATING SOLUTION BAUSCH + LOMB IRELAND LIMITED (IE) 2024-06-27 WO claimed
CN-116981761-A Contact lens treatment solution 博士伦爱尔兰有限公司 2023-10-31 CN claimed
EP-2699246-B1 METHOD OF INHIBITING HARMFUL MICROORGANISMS AND BARRIER-FORMING COMPOSITION THEREFOR ARMS Pharmaceutical LLC (US) 2023-06-14 EP claimed
CN-115916352-A Oral care compositions 高露洁-棕榄公司 2023-04-04 CN claimed
US-20230019880-A1 COMPOSITIONS JVS Products Ltd. (GB) 2023-01-19 US claimed
CN-107106663-B Compositions and kits for enzymatic debridement and methods of use thereof 罗查尔科技有限责任公司 2022-12-06 CN claimed
CN-110167667-B Microcapsules 科勒纸业公司 2022-09-20 CN claimed
US-20220288135-A1 LIVE BIOTHERAPEUTIC COMPOSITIONS AND METHODS BioPlx, Inc. (US) 2022-09-15 US claimed
CN-114452435-B High-affinity liquid dressing capable of being rapidly effective 浙江蓝智生物科技有限公司 2022-09-09 CN claimed
WO-1997019164-A1 NEAR TRICRITICAL POINT COMPOSITIONS COLGATE-PALMOLIVE COMPANY (US) 1997-05-29 WO claimed
WO-1997006782-A1 COMPOSITIONS INCLUDING O-CARBOXYALKYL CHITOSAN AND METHODS OF USE IN OPHTHALMICS NOVARTIS AG (CH) 1997-02-27 WO claimed
WO-1997000669-A1 COMPOSITIONS AND METHODS FOR STABILIZING POLYMERS NOVARTIS AG (CH) 1997-01-09 WO claimed
WO-1997000076-A1 COMPOSITIONS CONTAINING POLY(HEXAMETHYLENE BIGUANIDE) SALTS AND USES THEREOF MOORFIELDS EYE HOSPITAL (GB) 1997-01-03 WO claimed
EP-0384666-B1 Method and composition for cleaning and disinfecting contact lenses BAUSCH & LOMB (US) 1994-11-09 EP claimed
CN-1090129-A With containing PVP-H 2O 2Compositions-treated connect eyeglass BAUSCH & LOMB (US) 1994-08-03 CN claimed
US-5096607-A Using an aqueous system of a microbiocide of polyquaternized ammonium salts or biguanides and a proteolytic enzyme wherein the osmotic value is adjusted BAUSCH & LOMB INCORPORATED (US) 1992-03-17 US claimed
CN-1051841-A CONTACT LENS DISINFECTING SYSTEM SCHERING CORP (US) 1991-06-05 CN claimed
US-4654208-A Anti-microbial compositions comprising an aqueous solution of a germicidal polymeric nitrogen compound and a potentiating oxidizing agent STOCKEL RICHARD F 1987-03-31 US claimed
US-4499077-A AQUEOUS STABILIZED CHLORINE DIOXIDE AND A CATIONIC POLYMER OR A POLYGUANIDE; SOFT CANTACT LENSES;NONIRRITATING STOCKEL RICHARD F 1985-02-12 US claimed