Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 16/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4501220 | 0.90 | CTSA (0.40) | CTSACASP1 | |
| SCHEMBL4487148 | 0.88 | CTSA (0.42) | CTSACASP1 | |
| SCHEMBL4498480 | 0.82 | CASP1 (0.40) | CTSACASP1 | |
| SCHEMBL4492735 | 0.81 | CASP1 (0.43) | CTSACASP1NPSR1 | |
| SCHEMBL4480295 | 0.81 | CTSA (0.41) | CTSA | |
| SCHEMBL4495117 | 0.81 | CTSA (0.40) | CTSA | |
| SCHEMBL4500155 | 0.80 | CTSA (0.44) | CTSA | |
| SCHEMBL4495124 | 0.79 | LMNA (0.42) | CTSAHTT | |
| SCHEMBL4508505 | 0.79 | HTT (0.41) | CTSAHTT | |
| SCHEMBL4487757 | 0.79 | MAPT (0.38) | CTSAAURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541472-B2 | 3-Aryl-3-hydroxy-2-methylenepropionic acid esters as fungicides | CROPSOLUTION, INC. (US) | 2009-06-02 | — | — | US | disclosed |
| US-7541472-B2 | 3-Aryl-3-hydroxy-2-methylenepropionic acid esters as fungicides | CROPSOLUTION, INC. (US) | 2009-06-02 | — | — | US | disclosed |
| US-7541472-B2 | 3-Aryl-3-hydroxy-2-methylenepropionic acid esters as fungicides | CROPSOLUTION, INC. (US) | 2009-06-02 | — | — | US | disclosed |
| US-20060094739-A1 | 3-Aryl-3-hydroxy-2-methylenepropionic acid esters as fungicides | ATP CAPITAL LP | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094739-A1 | 3-Aryl-3-hydroxy-2-methylenepropionic acid esters as fungicides | CYP51A1, DDT, CYP21A2 | CTSA 1423/4885CASP1 443/4885HTT 1382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.