Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 2/20 | 0.36 |
| ▸ | CETP | P11597 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.35 |
| ▸ | LTC4S | Q16873 | 4/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | TACR1 | P25103 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4506119 | 0.92 | CETP (0.36) | CRHR1CETPLTC4SPIK3CDTACR1 | |
| SCHEMBL4514061 | 0.86 | CETP (0.39) | CRHR1CETPPIK3CD | |
| SCHEMBL14602964 | 0.84 | CRHR1 (0.35) | CRHR1CETPS1PR1LTC4SPIK3CD | |
| SCHEMBL14472674 | 0.83 | PIK3CD (0.34) | CETPS1PR1LTC4SPIK3CDTACR1 | |
| SCHEMBL14602966 | 0.81 | TACR1 (0.36) | CRHR1CETPS1PR1LTC4SPIK3CD | |
| SCHEMBL4496365 | 0.81 | CETP (0.43) | CRHR1CETPLTC4STACR1 | |
| SCHEMBL14602962 | 0.81 | CETP (0.38) | CETPS1PR1LTC4SPIK3CDTACR1 | |
| SCHEMBL17414304 | 0.81 | CRHR1 (0.33) | CRHR1S1PR1LTC4SPIK3CDTACR1 | |
| SCHEMBL17414298 | 0.80 | PIK3CD (0.33) | CRHR1CETPS1PR1LTC4SPIK3CD | |
| SCHEMBL4490162 | 0.78 | CETP (0.44) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090023729-A1 | Trisubstituted amine compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023729-A1 | Trisubstituted amine compound | CETP, MTTP, APOB | CRHR1 3834/4885CETP 1/4885S1PR1 1451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.