SCHEMBL4504686

SCHEMBL4504686

CC(C)(C)OC(=O)N1CCC(CCN2CCCN(c3ccc(S(C)(=O)=O)cc3)CC2)CC1

nearest known ligand 0.69

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 18/20 0.69
TGFBR1 P36897 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4514525 0.96 GPR119 (0.74) GPR119TGFBR1
SCHEMBL4516005 0.91 GPR119 (0.67) GPR119TGFBR1
SCHEMBL4512522 0.91 GPR119 (0.70) GPR119
SCHEMBL4524985 0.87 GPR119 (0.61) GPR119TGFBR1
SCHEMBL4513931 0.87 GPR119 (0.61) GPR119TGFBR1
SCHEMBL4503463 0.87 GPR119 (0.61) GPR119TGFBR1
SCHEMBL4513535 0.87 GPR119 (0.72) GPR119TGFBR1
Hydrochloric Acid SCHEMBL4507662 0.86 GPR119 (0.60) GPR119TGFBR1
SCHEMBL13757780 0.85 GPR119 (0.59) GPR119TGFBR1
SCHEMBL4520808 0.85 GPR119 (0.56) GPR119TGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090203676-A1 G-protein Coupled Receptor Agonists PROSIDION LIMITED (GB) 2009-08-13 US disclosed
US-20090203676-A1 G-protein Coupled Receptor Agonists PROSIDION LIMITED (GB) 2009-08-13 US disclosed
US-20090203676-A1 G-protein Coupled Receptor Agonists PROSIDION LIMITED (GB) 2009-08-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090203676-A1 G-protein Coupled Receptor Agonists GPR119, GCGR, GPBAR1 GPR119 1/4885TGFBR1 834/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.