Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 17/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4516005 | 0.96 | GPR119 (0.67) | GPR119MEN1KMT2ATGFBR1ALDH1A1 | |
| SCHEMBL4514525 | 0.91 | GPR119 (0.74) | GPR119MEN1KMT2ATGFBR1 | |
| SCHEMBL4512522 | 0.90 | GPR119 (0.70) | GPR119MEN1KMT2A | |
| SCHEMBL4504686 | 0.87 | GPR119 (0.69) | GPR119TGFBR1 | |
| SCHEMBL4520117 | 0.86 | GPR119 (0.71) | GPR119MEN1KMT2ATGFBR1ALDH1A1 | |
| SCHEMBL21877150 | 0.86 | GPR119 (0.56) | GPR119TGFBR1ALDH1A1LMNAMAPT | |
| SCHEMBL4512583 | 0.85 | GPR119 (0.70) | GPR119MEN1KMT2A | |
| SCHEMBL29986651 | 0.85 | MAPT (0.75) | GPR119MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL3923864 | 0.85 | GPR119 (0.79) | GPR119MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL4516970 | 0.85 | GPR119 (0.61) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203676-A1 | G-protein Coupled Receptor Agonists | PROSIDION LIMITED (GB) | 2009-08-13 | — | — | US | disclosed |
| US-20090203676-A1 | G-protein Coupled Receptor Agonists | PROSIDION LIMITED (GB) | 2009-08-13 | — | — | US | disclosed |
| US-20090203676-A1 | G-protein Coupled Receptor Agonists | PROSIDION LIMITED (GB) | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203676-A1 | G-protein Coupled Receptor Agonists | GPR119, GCGR, GPBAR1 | GPR119 1/4885MEN1 4300/4885KMT2A 4508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.