Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.56 |
| ▸ | BCL9 | O00512 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | RBP4 | P02753 | 2/20 | 0.35 |
| ▸ | HTR1D | P28221 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4503323 | 1.00 | IKBKB (0.56) | IKBKBBCL9CTNNB1RBP4HTR1D | |
| SCHEMBL7018884 | 1.00 | IKBKB (0.56) | IKBKBBCL9CTNNB1RBP4HTR1D | |
| SCHEMBL13936031 | 0.92 | IKBKB (0.53) | IKBKBBCL9CTNNB1ALDH1A1HTT | |
| SCHEMBL4504338 | 0.92 | IKBKB (0.53) | IKBKBBCL9CTNNB1ALDH1A1HTT | |
| SCHEMBL13936043 | 0.92 | IKBKB (0.53) | IKBKBBCL9CTNNB1ALDH1A1HTT | |
| SCHEMBL14599567 | 0.84 | IKBKB (0.46) | IKBKBBCL9CTNNB1ALDH1A1HTT | |
| SCHEMBL13954961 | 0.84 | IKBKB (0.50) | IKBKBALDH1A1HPGD | |
| SCHEMBL5568747 | 0.81 | IKBKB (0.47) | IKBKBHTR1DPDE10AGPR84 | |
| SCHEMBL4947847 | 0.81 | PRMT5 (0.42) | IKBKBBCL9CTNNB1HTT | |
| SCHEMBL14599370 | 0.81 | PRMT5 (0.42) | IKBKBBCL9CTNNB1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054424-A1 | Optically active pyridine derivative and a medicament containing the same | MURATA TOSHIKI | 2009-02-26 | — | — | US | disclosed |
| US-7375103-B2 | Optically active pyridine derivative and a medicament containing the same | BAYER HEALTHCARE AG (DE) | 2008-05-20 | — | — | US | disclosed |
| EP-1487842-B1 | AN OPTICALLY ACITVE PYRIDINE DERIVATIVE AND A MEDICAMENT CONTAINING THE SAME | BAYER HEALTHCARE AG (DE) | 2007-03-14 | — | — | EP | disclosed |
| US-20050215547-A1 | Optically active pyridine derivative and a medicament containing the same | BAYER HEALTHCARE AG (DE) | 2005-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054424-A1 | Optically active pyridine derivative and a medicament containing the same | IL1B, NFKBIA, IL17A | IKBKB 28/4885BCL9 2296/4885CTNNB1 728/4885 |
| US-20050215547-A1 | Optically active pyridine derivative and a medicament containing the same | IL1B, NFKBIA, IL1A | IKBKB 25/4885BCL9 2206/4885CTNNB1 707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.