Gentisic Acid

Gentisic Acid

SCHEMBL450480

O=C(O)c1cc(O)ccc1O.[NaH]

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.95
CA2 P00918 4/20 0.95
CA12 O43570 3/20 0.95
CA7 P43166 3/20 0.95
CA9 Q16790 3/20 0.95
CA14 Q9ULX7 3/20 0.95
PTGS2 P35354 3/20 0.95
ALOX5 P09917 1/20 0.95
ALDH1A1 P00352 3/20 0.64
TSHR P16473 1/20 0.64
MEN1 O00255 2/20 0.59
KDR P35968 2/20 0.59
KMT2A Q03164 2/20 0.59
HSD17B10 Q99714 2/20 0.59
TDP1 Q9NUW8 2/20 0.59
KDM4E B2RXH2 1/20 0.59
TNF P01375 1/20 0.59
CYP3A4 P08684 1/20 0.59
HSPD1 P10809 1/20 0.59
THRB P10828 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Gentisic Acid SCHEMBL8084110 0.98 CA1 (0.91) CA1CA2CA12CA7CA9
Gentisic Acid SCHEMBL3690 0.98 CA1 (1.00) CA1CA2CA12CA7CA9
Gentisic Acid SCHEMBL29349919 0.98 CA1 (1.00) CA1CA2CA12CA7CA9
Gentisic Acid SCHEMBL30233582 0.98 CA1 (1.00) CA1CA2CA12CA7CA9
Gentisic Acid SCHEMBL2053863 0.98 CA1 (1.00) CA1CA2CA12CA7CA9
Gentisic Acid SCHEMBL10980548 0.95 CA1 (0.95) CA1CA2CA12CA7CA9
Gentisic Acid SCHEMBL455606 0.95 CA1 (0.95) CA1CA2CA12CA7CA9
Gentisic Acid SCHEMBL10975219 0.95 CA1 (0.95) CA1CA2CA12CA7CA9
Gentisic Acid SCHEMBL344389 0.95 CA1 (0.95) CA1CA2CA12CA7CA9
Gentisic Acid SCHEMBL10978035 0.95 CA1 (0.95) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111712265-B Diagnostic composition for PET imaging, method for producing the same and use thereof in diagnosis AC免疫有限公司 2024-02-09 CN claimed
US-20210179975-A1 COMPOSITION CONTAINING LANTHANIDE METAL COMPLEX SPECIALTY OPERATIONS FRANCE (FR) 2021-06-17 US claimed
EP-3743115-A1 DIAGNOSTIC COMPOSITIONS FOR PET IMAGING, A METHOD FOR MANUFACTURING THE DIAGNOSTIC COMPOSITION AND ITS USE IN DIAGNOSTICS AC Immune SA (CH) 2020-12-02 EP claimed
WO-2019145293-A1 DIAGNOSTIC COMPOSITIONS FOR PET IMAGING, A METHOD FOR MANUFACTURING THE DIAGNOSTIC COMPOSITION AND ITS USE IN DIAGNOSTICS AC IMMUNE SA (CH) 2019-08-01 WO claimed
US-20190169667-A1 METHODS OF DECREASING TRISULFIDE BONDS DURING RECOMBINANT PRODUCTION OF POLYPEPTIDES GENENTECH, INC. (US) 2019-06-06 US claimed
EP-3455364-A2 METHODS OF DECREASING TRISULFIDE BONDS DURING RECOMBINANT PRODUCTION OF POLYPEPTIDES H. Hoffnabb-La Roche Ag (CH) 2019-03-20 EP claimed
WO-2017196902-A2 METHODS OF DECREASING TRISULFIDE BONDS DURING RECOMBINANT PRODUCTION OF POLYPEPTIDES GENENTECH, INC. (US) 2017-11-16 WO claimed
US-12616738-B2 Solid compositions comprising a GLP-1 agonist and a salt of N-(8-(2-hydroxybenzoyl)amino)caprylic acid NOVO NORDISK A/S (DK) 2026-05-05 US disclosed
US-20260008997-A1 CELL CULTURE COMPOSITIONS WITH ANTIOXIDANTS AND METHODS FOR POLYPEPTIDE PRODUCTION GENENTECH, INC. (US) 2026-01-08 US disclosed
EP-2970875-B2 CELL CULTURE COMPOSITIONS WITH ANTIOXIDANTS AND METHODS FOR POLYPEPTIDE PRODUCTION HOFFMANN LA ROCHE (CH) 2025-11-26 EP disclosed
US-20250186600-A1 EXCIPIENT COMPOUNDS FOR PROTEIN FORMULATIONS COMERA LIFE SCIENCES, INC. 2025-06-12 US disclosed
WO-2024036372-A1 FORMULATIONS FOR RADIOTHERAPY AND DIAGNOSTIC IMAGING AND USE THEREOF IN TREATMENT, DIAGNOSIS AND IMAGING DISEASES Clarity Pharmaceuticals Limited (AU) 2024-02-22 WO disclosed
EP-4324482-A2 EXCIPIENT COMPOUNDS FOR BIOPOLYMER FORMULATIONS Comera Life Sciences, Inc. (US) 2024-02-21 EP disclosed
US-4470980-A Method of increasing oral absorption of β-lactam antibiotics INTERX RESEARCH CORP. (US) 1984-09-11 US disclosed
US-4464363-A HYDROXY ARYL- OR HYDROXY ARALKYL ACIDS OR SALTS MERCK & CO., INC. (US) 1984-08-07 US disclosed
US-4406896-A ANTIBIOTICS, ACIDS, HYDROXY MERCK & CO., INC. (US) 1983-09-27 US disclosed
EP-0036534-A1 An orally administrable drug form comprising a beta-lactam antibiotic and an adjuvant INTERx RESEARCH CORPORATION (US) 1981-09-30 EP disclosed
EP-0036145-A1 An orally administered drug form comprising a polar bioactive agent and an adjuvant INTERx RESEARCH CORPORATION (US) 1981-09-23 EP disclosed
EP-0035770-A2 An orally administered drug form comprising a glycosidic antibiotic and an adjuvant INTERx RESEARCH CORPORATION (US) 1981-09-16 EP disclosed
EP-0031561-A2 A rectally administered suppository comprising a drug and an adjuvant MERCK & CO. INC. (US) 1981-07-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12616738-B2 Solid compositions comprising a GLP-1 agonist and a salt of N-(8-(2-hydroxybenzoyl)amino)caprylic acid SLC5A1, GLP1R, SLC5A2 CA1 1173/4885CA2 335/4885CA12 1815/4885
US-20260008997-A1 CELL CULTURE COMPOSITIONS WITH ANTIOXIDANTS AND METHODS FOR POLYPEPTIDE PRODUCTION CD99, BHMT, PROC CA1 168/4885CA2 349/4885CA12 774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.