Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.53 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.53 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.53 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.53 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.53 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | GABRP | O00591 | 1/20 | 0.53 |
| ▸ | GABRD | O14764 | 1/20 | 0.53 |
| ▸ | IKBKB | O14920 | 1/20 | 0.53 |
| ▸ | AURKA | O14965 | 1/20 | 0.53 |
| ▸ | CHUK | O15111 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | TOP1 | P11387 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26976592 | 0.87 | CHUK (0.47) | TDO2SMN1; SMN2GABRA1GABRG2GABRB3 | |
| Quindoline SCHEMBL191243 | 0.82 | NPC1 (0.58) | SMN1; SMN2GABRA1GABRG2GABRB3GABRA5 | |
| Quindoline SCHEMBL30805772 | 0.82 | NPC1 (0.58) | SMN1; SMN2GABRA1GABRG2GABRB3GABRA5 | |
| Quindoline SCHEMBL8481282 | 0.80 | NPC1 (0.56) | SMN1; SMN2GABRA1GABRG2GABRB3GABRA5 | |
| Quindoline SCHEMBL8478837 | 0.80 | NPC1 (0.56) | SMN1; SMN2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL17274958 | 0.78 | SMN1; SMN2 (0.53) | TDO2SMN1; SMN2GABRA1GABRG2GABRB3 | |
| SCHEMBL30704451 | 0.75 | SMN1; SMN2 (0.73) | TDO2SMN1; SMN2GABRA1GABRG2GABRB3 | |
| SCHEMBL30646327 | 0.75 | SMN1; SMN2 (0.73) | TDO2SMN1; SMN2GABRA1GABRG2GABRB3 | |
| SCHEMBL824397 | 0.75 | SMN1; SMN2 (0.73) | TDO2SMN1; SMN2GABRA1GABRG2GABRB3 | |
| SCHEMBL824357 | 0.75 | SMN1; SMN2 (0.73) | TDO2SMN1; SMN2GABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252814-B2 | Agents and crystals for improving excretory potency of urinary bladder | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-08-28 | — | — | US | disclosed |
| US-20090264467-A1 | Agents and crystals for improving excretory potency of urinary bladder | ISHIHARA YUJI | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264467-A1 | Agents and crystals for improving excretory potency of urinary bladder | ACHE, BCHE, PDE7A | TDO2 3829/4885SMN1; SMN2 2369/4885GABRA1 2795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.