Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | CASP1 | P29466 | 2/20 | 0.58 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.58 |
| ▸ | CASP7 | P55210 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | APAF1 | O14727 | 1/20 | 0.55 |
| ▸ | RAD52 | P43351 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | GPR3 | P46089 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quindoline SCHEMBL30805772 | 1.00 | NPC1 (0.58) | NPC1RAB9APOLBSMN1; SMN2TP53 | |
| Quindoline SCHEMBL8478837 | 0.98 | NPC1 (0.56) | NPC1RAB9APOLBSMN1; SMN2TP53 | |
| Quindoline SCHEMBL8481282 | 0.98 | NPC1 (0.56) | NPC1RAB9APOLBSMN1; SMN2TP53 | |
| Acridine SCHEMBL28191835 | 0.82 | ALDH1A1 (0.62) | NPC1RAB9APOLBSMN1; SMN2TP53 | |
| SCHEMBL4505367 | 0.82 | TDO2 (0.53) | NPC1RAB9APOLBSMN1; SMN2TP53 | |
| SCHEMBL8478861 | 0.82 | NPC1 (0.62) | NPC1RAB9APOLBSMN1; SMN2TP53 | |
| SCHEMBL2112432 | 0.82 | NPC1 (0.55) | NPC1RAB9APOLBSMN1; SMN2TP53 | |
| SCHEMBL24621698 | 0.80 | NPC1 (0.40) | NPC1RAB9APOLBSMN1; SMN2TP53 | |
| SCHEMBL633820 | 0.80 | PARP1 (0.53) | NPC1RAB9APOLBSMN1; SMN2TP53 | |
| SCHEMBL24621438 | 0.79 | NPC1 (0.39) | NPC1RAB9APOLBSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 447 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12559499-B2 | Uses of compounds having anti-HSV-1 activity | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2026-02-24 | — | — | US | claimed |
| CN-113956232-B | Quinoline-bisindole compound and preparation method and application thereof | 山东师范大学 | 2022-09-16 | — | — | CN | claimed |
| US-20220105083-A1 | USES OF COMPOUNDS HAVING ANTI-HSV-1 ACTIVITY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-04-07 | — | — | US | claimed |
| CN-113956232-A | Quinoline-bisindole compound and preparation method and application thereof | 山东师范大学 | 2022-01-21 | — | — | CN | claimed |
| WO-2021105761-A1 | COMPOSITIONS AND THEIR USES FOR TREATING CANCERS | INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (INSERM) (FR) | 2021-06-03 | — | — | WO | claimed |
| WO-2020160174-A1 | USES OF COMPOUNDS HAVING ANTI-HSV-1 ACTIVITY | UNIVERSITA DEGLI STUDI DI PADOVA (IT) | 2020-08-06 | — | — | WO | claimed |
| CN-108752339-B | A kind of synthetic method of quindoline and its derivative | 武汉工程大学 | 2019-10-22 | — | — | CN | claimed |
| CN-108752339-A | A kind of synthetic method of quindoline and its derivative | 武汉工程大学 | 2018-11-06 | — | — | CN | claimed |
| CN-108558878-A | A kind of synthesis technology of quindoline and its derivative | 武汉工程大学 | 2018-09-21 | — | — | CN | claimed |
| US-9960356-B2 | Organic electroluminescence device, lighting equipment and display device | Konica Minolta, Inc. (JP) | 2018-05-01 | — | — | US | claimed |
| US-20150166886-A1 | FLUORESCENCE AND DELAYED FLUORESCENCE-TYPE ORGANIC LIGHT-EMITTING MATERIAL AND ELEMENT | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2015-06-18 | — | — | US | claimed |
| US-7439271-B2 | Reduction of hair growth | THE GILLETTE COMPANY (US) | 2008-10-21 | — | — | US | claimed |
| US-20030012755-A1 | Reduction of hair growth | GILLETTE COMPANY, THE | 2003-01-16 | — | — | US | claimed |
| WO-1994018203-A1 | ALKALOID COMPOUNDS EXTRACTED FROM CRYPTOLEPIS SANQUINOLENTA AND USES THEREOF | HEALTHSEARCH, INC. (US) | 1994-08-18 | — | — | WO | claimed |
| US-20260114114-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT AND COMPOSITION FOR ORGANIC MATERIALS | MERCK PATENT GMBH (DE) | 2026-04-23 | — | — | US | disclosed |
| US-12559499-B2 | Uses of compounds having anti-HSV-1 activity | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2026-02-24 | — | — | US | disclosed |
| US-12559459-B2 | Aromatic heterocyclic derivative, and organic electroluminescent element, illumination device, and display device using aromatic heterocyclic derivative | MERCK PATENT GMBH (DE) | 2026-02-24 | — | — | US | disclosed |
| WO-1996010015-A1 | CRYPTOLEPINE ANALOGS WITH HYPOGLYCEMIC ACTIVITY | SHAMAN PHARMACEUTICALS, INC. (US) | 1996-04-04 | — | — | WO | disclosed |
| US-5362726-A | Spiro-nonacyclic indoloquinoline alkaloid, cryptospirolepine | HEALTHSEARCH, INC. (US) | 1994-11-08 | — | — | US | disclosed |
| WO-1994018203-A1 | ALKALOID COMPOUNDS EXTRACTED FROM CRYPTOLEPIS SANQUINOLENTA AND USES THEREOF | HEALTHSEARCH, INC. (US) | 1994-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220105083-A1 | USES OF COMPOUNDS HAVING ANTI-HSV-1 ACTIVITY | HDAC1, HDAC7, HDAC6 | NPC1 1011/4885RAB9A 1440/4885POLB 685/4885 |
| US-12559459-B2 | Aromatic heterocyclic derivative, and organic electroluminescent element, illumination device, and display device using aromatic heterocyclic derivative | NR2E3, CDYL, TYR | NPC1 4735/4885RAB9A 2749/4885POLB 4344/4885 |
| US-20260114114-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT AND COMPOSITION FOR ORGANIC MATERIALS | LEF1, AP2A1, CACNA2D1 | NPC1 3746/4885RAB9A 3751/4885POLB 1552/4885 |
| US-20150166886-A1 | FLUORESCENCE AND DELAYED FLUORESCENCE-TYPE ORGANIC LIGHT-EMITTING MATERIAL AND ELEMENT | LEF1, EML4, TEAD1 | NPC1 3075/4885RAB9A 4391/4885POLB 3255/4885 |
| US-12559499-B2 | Uses of compounds having anti-HSV-1 activity | TOP1, CDK7, TOP2B | NPC1 2537/4885RAB9A 1041/4885POLB 126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.