Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.57 |
| ▸ | NPC1 | O15118 | 7/20 | 0.57 |
| ▸ | RAB9A | P51151 | 7/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MRGPRX4 | Q96LA9 | 8/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.47 |
| ▸ | GCK | P35557 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4516452 | 0.86 | SMN1; SMN2 (0.63) | SMN1; SMN2NPC1RAB9AMAPTHPGD | |
| Trifluoroacetic Acid SCHEMBL4511157 | 0.83 | SMN1; SMN2 (0.64) | SMN1; SMN2NPC1RAB9AMAPTHPGD | |
| Trifluoroacetic Acid SCHEMBL4502618 | 0.81 | SMN1; SMN2 (0.62) | SMN1; SMN2NPC1RAB9AMAPTHPGD | |
| Trifluoroacetic Acid SCHEMBL4508117 | 0.81 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1RAB9AMAPTHPGD | |
| Trifluoroacetic Acid SCHEMBL4505140 | 0.81 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1RAB9AMAPTHPGD | |
| Trifluoroacetic Acid SCHEMBL4503678 | 0.79 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1RAB9AMAPTHPGD | |
| SCHEMBL4505850 | 0.78 | SMN1; SMN2 (0.67) | SMN1; SMN2NPC1RAB9AMAPTHPGD | |
| SCHEMBL4509901 | 0.77 | SMN1; SMN2 (0.66) | SMN1; SMN2NPC1RAB9AMAPTHPGD | |
| SCHEMBL4505191 | 0.73 | SMN1; SMN2 (0.68) | SMN1; SMN2NPC1RAB9AMAPTHPGD | |
| SCHEMBL4506893 | 0.73 | SMN1; SMN2 (0.68) | SMN1; SMN2NPC1RAB9AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | SCD, SCD5, SMS | SMN1; SMN2 2075/4885NPC1 57/4885RAB9A 3368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.