Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4496717 | 0.90 | MAPT (0.60) | SMN1; SMN2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL4500386 | 0.89 | MAPT (0.74) | SMN1; SMN2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL4501168 | 0.84 | MAPT (0.60) | SMN1; SMN2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL4492876 | 0.84 | MAPT (0.52) | SMN1; SMN2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL4500960 | 0.83 | SMN1; SMN2 (0.58) | SMN1; SMN2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL4502419 | 0.82 | MAPT (0.59) | SMN1; SMN2MAPTMEN1KMT2AKDM4E | |
| Trifluoroacetic Acid SCHEMBL4508117 | 0.80 | SMN1; SMN2 (0.61) | SMN1; SMN2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL4516088 | 0.79 | SMN1; SMN2 (0.48) | SMN1; SMN2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL4513766 | 0.77 | MAPT (0.48) | SMN1; SMN2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL4491985 | 0.77 | MRGPRX4 (0.62) | SMN1; SMN2MAPTMEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | SCD, SCD5, SMS | SMN1; SMN2 2075/4885MAPT 4022/4885MEN1 4180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.