Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | NPC1 | O15118 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.56 |
| ▸ | DHODH | Q02127 | 3/20 | 0.56 |
| ▸ | SCD | O00767 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TOP1 | P11387 | 2/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4502413 | 0.81 | SMN1; SMN2 (0.68) | RAB9ASMN1; SMN2NPC1MAPTHPGD | |
| SCHEMBL4920234 | 0.80 | SCD (0.73) | RAB9ASMN1; SMN2NPC1DHODHSCD | |
| SCHEMBL30582460 | 0.77 | SCD (0.56) | RAB9ASMN1; SMN2NPC1MAPTHPGD | |
| SCHEMBL4917465 | 0.76 | TOP1 (0.70) | RAB9ASMN1; SMN2NPC1DHODHSCD | |
| SCHEMBL8642176 | 0.75 | SCD (0.65) | RAB9ASMN1; SMN2NPC1DHODHSCD | |
| SCHEMBL8642180 | 0.75 | SCD (0.65) | RAB9ASMN1; SMN2NPC1DHODHSCD | |
| SCHEMBL4505850 | 0.75 | SMN1; SMN2 (0.67) | RAB9ASMN1; SMN2NPC1MAPTHPGD | |
| SCHEMBL4506893 | 0.75 | SMN1; SMN2 (0.68) | RAB9ASMN1; SMN2NPC1MAPTHPGD | |
| SCHEMBL4509901 | 0.75 | SMN1; SMN2 (0.66) | RAB9ASMN1; SMN2NPC1MAPTHPGD | |
| SCHEMBL30553332 | 0.74 | NPC1 (0.78) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | SCD, SCD5, SMS | RAB9A 3368/4885SMN1; SMN2 2075/4885NPC1 57/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.