SCHEMBL451010

SCHEMBL451010

O=[N+]([O-])c1cnc[c]n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3296075 0.69 ALDH1A1 (0.36)
SCHEMBL9486037 0.65 CYP19A1 (0.39)
SCHEMBL448923 0.65
SCHEMBL563511 0.64
SCHEMBL7694711 0.61 ALDH1A1 (0.39)
SCHEMBL446364 0.61
SCHEMBL8065542 0.61 CDK2 (0.41)
SCHEMBL432543 0.59
SCHEMBL5252228 0.59 CYP19A1 (0.55)
SCHEMBL446901 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2375898-B1 NOVEL HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2015-09-16 EP claimed
WO-2008132211-A1 AMINO-QUINAZOLINONE DERIVATIVES FOR USE AS RADIOTRACERS AND IMAGING AGENTS NOVARTIS AG (CH) 2008-11-06 WO claimed
EP-2997824-A1 NOVEL HERBICIDES Syngenta Participations AG. (CH) 2016-03-23 EP disclosed
EP-2375898-B1 NOVEL HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2015-09-16 EP disclosed
CN-104193693-A NOVEL HERBICIDES SYNGENTA LTD 2014-12-10 CN disclosed
US-8889595-B2 Herbicides SYNGENTA PARTICIPATIONS AG (CH) 2014-11-18 US disclosed
US-20120065064-A1 NOVEL HERBICIDES SYNGENTA CROP PROTECTION LLC (US) 2012-03-15 US disclosed
CN-102300458-A New herbicides 2011-12-28 CN disclosed
WO-2008132211-A1 AMINO-QUINAZOLINONE DERIVATIVES FOR USE AS RADIOTRACERS AND IMAGING AGENTS NOVARTIS AG (CH) 2008-11-06 WO disclosed