⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27982911 | 0.85 | RAB9A (0.36) | — | |
| SCHEMBL30269895 | 0.73 | MAPT (0.42) | — | |
| SCHEMBL28365564 | 0.73 | MAPT (0.42) | — | |
| SCHEMBL3296075 | 0.72 | ALDH1A1 (0.36) | — | |
| SCHEMBL28423816 | 0.68 | CYP19A1 (0.38) | — | |
| SCHEMBL18879407 | 0.67 | HSP90AA1 (0.34) | — | |
| SCHEMBL11874665 | 0.67 | — | — | |
| SCHEMBL29542640 | 0.67 | — | — | |
| SCHEMBL33930 | 0.67 | — | — | |
| SCHEMBL3722614 | 0.66 | KDM4E (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119241450-A | Pyrazine compound and preparation method and application thereof, nitropyrazine compound and preparation method and application thereof, wu Pa tenib intermediate preparation method | 江西同和药业股份有限公司 | 2025-01-03 | — | — | CN | claimed |
| US-10224485-B2 | Process for preparing a crystalline organic semiconductor material | BASF SE (DE) | 2019-03-05 | — | — | US | claimed |
| US-20170012208-A1 | ORGANIC SEMICONDUCTOR FORMULATIONS | USINVEST LLC | 2017-01-12 | — | — | US | claimed |
| CN-102105623-B | Electrolytic gold plating solution and gold film obtained using same | JAPAN PURE CHEMICAL CO LTD | 2013-10-02 | — | — | CN | claimed |
| CN-102105623-A | Electrolytic gold plating solution and gold film obtained using same | JAPAN PURE CHEMICAL CO LTD | 2011-06-22 | — | — | CN | claimed |
| EP-0199096-B1 | NITRO SUBSTITUTED HETEROARYL COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1989-12-20 | — | — | EP | claimed |
| EP-0330201-A2 | Method of enhancing the effect of cytotoxic agents | NEORX CORPORATION (US) | 1989-08-30 | — | — | EP | claimed |
| EP-0111151-B1 | SUBSTITUTED NITROPYRAZINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1987-12-09 | — | — | EP | claimed |
| US-4709035-A | 2,6-disubstituted derivatives of 3-nitropyrazines useful as adjuncts to radiation therapy | MERCK & CO., INC. (US) | 1987-11-24 | — | — | US | claimed |
| EP-0199096-A1 | Nitro substituted heteroaryl compounds, process for their preparation and pharmaceutical compositions containing them | MERCK & CO. INC. (US) | 1986-10-29 | — | — | EP | claimed |
| US-4609659-A | 2,6-disubstituted derivatives of 3-nitropyrazines useful as adjuncts to radiation therapy | MERCK & CO., INC. (US) | 1986-09-02 | — | — | US | claimed |
| EP-0111151-A1 | Substituted nitropyrazine compounds, process for their preparation and pharmaceutical compositions containing them | MERCK & CO. INC. (US) | 1984-06-20 | — | — | EP | claimed |
| CN-119241450-B | Pyrazine compound and preparation method and application thereof, nitropyrazine compound and preparation method and application thereof, wu Pa tenib intermediate preparation method | 江西同和药业股份有限公司 | 2026-02-06 | — | — | CN | disclosed |
| CN-119241450-B | Pyrazine compound and preparation method and application thereof, nitropyrazine compound and preparation method and application thereof, wu Pa tenib intermediate preparation method | 江西同和药业股份有限公司 | 2026-02-06 | — | — | CN | disclosed |
| CN-119241450-A | Pyrazine compound and preparation method and application thereof, nitropyrazine compound and preparation method and application thereof, wu Pa tenib intermediate preparation method | 江西同和药业股份有限公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-119241450-A | Pyrazine compound and preparation method and application thereof, nitropyrazine compound and preparation method and application thereof, wu Pa tenib intermediate preparation method | 江西同和药业股份有限公司 | 2025-01-03 | — | — | CN | disclosed |
| EP-0096125-A1 | Amino and amido derivatives of chloro nitro amino and alkylamino pyrazines useful as adjuncts to radiation therapy | MERCK & CO. INC. (US) | 1983-12-21 | — | — | EP | disclosed |
| US-4418062-A | Amino derivatives of chloro nitro amino pyrazines useful as adjuncts to radiation therapy | MERCK & CO., INC. (US) | 1983-11-29 | — | — | US | disclosed |
| US-4416882-A | Di(alkylamino) derivatives of chloronitropyrazines useful as adjuncts to radiation therapy | MERCK & CO., INC. (US) | 1983-11-22 | — | — | US | disclosed |
| US-4414215-A | N-Acyl derivatives of 6-alkylamino 5-chloro-3-nitropyrazinamines for radiation therapy | MERCK & CO., INC. (US) | 1983-11-08 | — | — | US | disclosed |