Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | F12 | P00748 | 1/20 | 0.42 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL199273 | 0.75 | PLAU (0.60) | MAPTKDM4ENPC1RAB9AL3MBTL1 | |
| SCHEMBL29923403 | 0.75 | PLAU (0.60) | MAPTKDM4ENPC1RAB9AL3MBTL1 | |
| SCHEMBL1250423 | 0.74 | KDM4E (0.42) | MAPTKDM4ERAB9AL3MBTL1MAPK1 | |
| SCHEMBL216707 | 0.73 | — | — | |
| SCHEMBL30522769 | 0.73 | PLAU (0.58) | MAPTKDM4ENPC1RAB9AL3MBTL1 | |
| SCHEMBL2837559 | 0.73 | ADORA2A (0.51) | MAPTNPC1RAB9AL3MBTL1KMT2A | |
| SCHEMBL1288464 | 0.72 | KMT2A (0.49) | MAPTKDM4ENPC1RAB9AL3MBTL1 | |
| SCHEMBL31595661 | 0.72 | KMT2A (0.49) | MAPTKDM4ENPC1RAB9AL3MBTL1 | |
| SCHEMBL27884143 | 0.72 | MAPT (0.45) | MAPTKDM4ENPC1RAB9AL3MBTL1 | |
| SCHEMBL12223316 | 0.72 | PLAU (0.56) | MAPTKDM4ENPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016187521-A1 | 5-SUBSTITUTED 1 H-TETRAZOLE COMPOUNDS, METHODS OF SYNTHESIZING AND THERAPEUTIC USE | SOUTH CONNECTICUT STATE UNIVERSITY (US) | 2016-11-24 | — | — | WO | disclosed |
| US-9266906-B2 | Copper(I) complexes for optoelectronic devices | CYNORA GMBH (DE) | 2016-02-23 | — | — | US | disclosed |
| US-9266906-B2 | Copper(I) complexes for optoelectronic devices | CYNORA GMBH (DE) | 2016-02-23 | — | — | US | disclosed |
| EP-2729477-B1 | COPPER(I) COMPLEXES FOR OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2016-01-20 | — | — | EP | disclosed |
| US-20140235006-A1 | COPPER(I) COMPLEXES FOR OPTOELECTRONIC DEVICES | SAMSUNG DISPLAY CO., LTD. (KR) | 2014-08-21 | — | — | US | disclosed |
| US-20140235006-A1 | COPPER(I) COMPLEXES FOR OPTOELECTRONIC DEVICES | SAMSUNG DISPLAY CO., LTD. (KR) | 2014-08-21 | — | — | US | disclosed |
| US-8802861-B2 | Thiazole derivatives and use thereof | MERCK SERONO SA (CH) | 2014-08-12 | — | — | US | disclosed |
| US-7906038-B2 | Aqueous polishing liquid and chemical mechanical polishing method | FUJIFILM CORPORATION (JP) | 2011-03-15 | — | — | US | disclosed |
| US-7906038-B2 | Aqueous polishing liquid and chemical mechanical polishing method | FUJIFILM CORPORATION (JP) | 2011-03-15 | — | — | US | disclosed |
| US-7547335-B2 | Metal polishing composition and method of polishing using the same | FUJIFILM CORPORATION (JP) | 2009-06-16 | — | — | US | disclosed |
| US-7547335-B2 | Metal polishing composition and method of polishing using the same | FUJIFILM CORPORATION (JP) | 2009-06-16 | — | — | US | disclosed |
| US-20090029998-A1 | Thiazole Derivatives and Use Thereof | APPLIED RESEARCH SYSTEM ARS HOLDING N.V. (NL) | 2009-01-29 | — | — | US | disclosed |
| US-20070287362-A1 | POLISHING COMPOSITION AND METHOD OF POLISHING WITH THE SAME | FUJIFILM CORPORATION | 2007-12-13 | — | — | US | disclosed |
| US-20070287362-A1 | POLISHING COMPOSITION AND METHOD OF POLISHING WITH THE SAME | FUJIFILM CORPORATION | 2007-12-13 | — | — | US | disclosed |
| US-20070069176-A1 | Aqueous polishing liquid and chemical mechanical polishing method | FUJI PHOTO FILM CO., LTD. | 2007-03-29 | — | — | US | disclosed |
| US-20070069176-A1 | Aqueous polishing liquid and chemical mechanical polishing method | FUJI PHOTO FILM CO., LTD. | 2007-03-29 | — | — | US | disclosed |
| EP-1615894-A2 | 3-AZABICYCLO 3.2.1 OCTANE DERIVATIVES | Pfizer Products Inc. (US) | 2006-01-18 | — | — | EP | disclosed |
| EP-1615643-A1 | 4-PHENYL-PIPERIDINE COMPOUNDS AND THEIR USE AS MODULATORS OF OPIOID RECEPTORS | Pfizer Products Inc. (US) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004089370-A1 | 4-PHENYL-PIPERIDINE COMPOUNDS AND THEIR USE AS MODULATORS OF OPIOID RECEPTORS | PFIZER PRODUCTS INC. (US) | 2004-10-21 | — | — | WO | disclosed |
| WO-2004089908-A2 | 3-AZABICYCLO[3.2.1]OCTANE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2004-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029998-A1 | Thiazole Derivatives and Use Thereof | PDGFRB, PDGFRA, TEC | MAPT 1418/4885KDM4E 4801/4885NPC1 3530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.