Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29191941 | 0.85 | CTSK (0.52) | EPHX1EPHX2CTSKCYP2C9HSD11B1 | |
| SCHEMBL12276428 | 0.85 | EPHX1 (0.46) | EPHX1CTSKCYP2C9HSD11B1GAA | |
| SCHEMBL3169231 | 0.84 | EPHX2 (0.47) | EPHX1EPHX2CTSKCYP2C9HSD11B1 | |
| SCHEMBL13208 | 0.84 | EPHX1 (0.58) | EPHX1EPHX2CTSKCYP2C9HSD11B1 | |
| Acetic Acid SCHEMBL25356110 | 0.81 | EPHX1 (0.56) | EPHX1EPHX2CYP2C9HSD11B1ALDH1A1 | |
| SCHEMBL8202964 | 0.81 | EPHX1 (0.43) | EPHX1CTSKCYP2C9HSD11B1GAA | |
| SCHEMBL12539827 | 0.80 | CTSK (0.46) | EPHX1CTSKCYP2C9HSD11B1GAA | |
| SCHEMBL13999540 | 0.80 | HSD11B1 (0.57) | EPHX1CTSKCYP2C9HSD11B1CA1 | |
| SCHEMBL18061088 | 0.80 | CA1 (0.49) | EPHX1CTSKCYP2C9HSD11B1GAA | |
| SCHEMBL18061103 | 0.79 | HSD11B1 (0.47) | EPHX1CTSKCYP2C9HSD11B1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8232286-B2 | N-[1-(3-dimethylamino-4-formyl-phenyl)-3-pyridin-3-yl-4,5-dihydro-1H-pyrazolo[4,3-g]benzothiazol-7-yl]-acetamide; phosphatidylinositol-3-kinases (PI3-kinases) inhibitor; cell growth, differentiation and intracellular transport processes; antiproliferative, antiinflammatory agent; autoimmune diseases | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-07-31 | — | — | US | disclosed |
| US-20090156554-A1 | P13-KINASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-06-18 | — | — | US | disclosed |
| US-20060106013-A1 | PI3-kinases | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156554-A1 | P13-KINASES | PIK3C3, PDPK1, MAP3K13 | EPHX1 3488/4885KDM1A 4330/4885EPHX2 3883/4885 |
| US-20060106013-A1 | PI3-kinases | PIK3C3, PIK3CB, PIK3CD | EPHX1 3760/4885KDM1A 4014/4885EPHX2 4266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.