SCHEMBL4510358

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3491807	0.85	PDE5A (0.56)	PDE5AALDH1A1KDM4ESMN1; SMN2MEN1
	SCHEMBL4521870	0.83	KMT2A (0.58)	ALDH1A1KDM4EGAAHPGDTSHR
	SCHEMBL3494101	0.82	PDE5A (0.55)	PDE5AALDH1A1KDM4ESMN1; SMN2MEN1
	SCHEMBL3491252	0.80	PDE5A (0.61)	PDE5AALDH1A1KDM4ESMN1; SMN2MEN1
	SCHEMBL4520288	0.80	KMT2A (0.57)	ALDH1A1KDM4EGAAHPGDTSHR
	SCHEMBL4511837	0.78	PDE5A (0.50)	PDE5AALDH1A1KDM4EGAAHPGD
	SCHEMBL4530199	0.77	SMN1; SMN2 (0.50)	PDE5AALDH1A1KDM4ETSHRSMN1; SMN2
	SCHEMBL4522382	0.77	PDE5A (0.57)	PDE5AALDH1A1KDM4EGAAHPGD
	SCHEMBL21153553	0.77	PDE5A (0.37)	PDE5AALDH1A1KDM4ESMN1; SMN2MEN1
	SCHEMBL4515609	0.76	PDE5A (0.76)	PDE5AALDH1A1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.