SCHEMBL3491807

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3494101	0.97	PDE5A (0.55)	PDE5ABRD4SMN1; SMN2KMT2ARAB9A
	SCHEMBL4510358	0.85	PDE5A (0.44)	PDE5ASMN1; SMN2KMT2AMEN1ALDH1A1
	SCHEMBL21153553	0.82	PDE5A (0.37)	PDE5ABRD4SMN1; SMN2KMT2ARAB9A
	SCHEMBL38093	0.79	PDE5A (0.55)	PDE5ASMN1; SMN2RAB9ANPC1ALDH1A1
	SCHEMBL3491566	0.79	ALDH1A1 (0.53)	SMN1; SMN2KMT2ARAB9AMEN1NPC1
	SCHEMBL3494163	0.77	PDE5A (0.79)	PDE5ABRD4SMN1; SMN2KMT2ARAB9A
	SCHEMBL3491341	0.76	ALDH1A1 (0.52)	BRD4SMN1; SMN2KMT2ARAB9AMEN1
	SCHEMBL13620444	0.75	PDE5A (0.54)	PDE5AKMT2ARAB9AMEN1NPC1
	SCHEMBL16175565	0.75	ALDH1A1 (0.42)	BRD4SMN1; SMN2KMT2AMEN1ALDH1A1
	SCHEMBL3492972	0.74	PDE5A (0.67)	PDE5ABRD4SMN1; SMN2KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.