SCHEMBL9000784

SCHEMBL9000784

C=CCOC(NC(=O)C=C)C(=O)OC

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.44
MAPT P10636 3/20 0.35
CACNA1B Q00975 1/20 0.35
APBA1 Q02410 1/20 0.35
ALDH1A1 P00352 3/20 0.33
TDP1 Q9NUW8 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
MAPK1 P28482 1/20 0.33
TGM2 P21980 2/20 0.32
ACACB O00763 2/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL253106 0.89 TSHR (0.44) TSHRMAPTCACNA1BAPBA1ALDH1A1
SCHEMBL9262683 0.84 TSHR (0.45) TSHRALDH1A1TDP1MEN1KMT2A
SCHEMBL9004289 0.84 TSHR (0.45) TSHRMAPTCACNA1BAPBA1ALDH1A1
SCHEMBL9257778 0.81 TSHR (0.42) TSHRMAPTALDH1A1TDP1MEN1
SCHEMBL451042 0.79 TSHR (0.52) TSHRALDH1A1TDP1MEN1KMT2A
SCHEMBL9286940 0.79 TSHR (0.44) TSHRMAPTCACNA1BAPBA1ALDH1A1
SCHEMBL9000273 0.78 TSHR (0.47) TSHRMAPTALDH1A1TGM2ACACB
SCHEMBL9000788 0.76 TSHR (0.41) TSHRMAPTCACNA1BAPBA1ALDH1A1
SCHEMBL11393628 0.76 TSHR (0.43) TSHRMAPTCACNA1BAPBA1ALDH1A1
SCHEMBL8041733 0.74 TSHR (0.47) TSHRALDH1A1TDP1MAPK1TGM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0435635-B1 Electrically conductive layer for electrical devices XEROX CORP (US) 1996-09-18 EP claimed
EP-0435633-B1 Electrically conductive layer for electrical devices XEROX CORP (US) 1996-09-11 EP claimed
US-5063128-A Forming a semitransparent conductive layer of particles having acidic surfaces and a polymer; xerography; humidity resistance; durability XEROX CORPORATION (US) 1991-11-05 US claimed
US-5063125-A For electrographic imaging XEROX CORPORATION (US) 1991-11-05 US claimed
EP-0435633-A2 Electrically conductive layer for electrical devices XEROX CORPORATION (US) 1991-07-03 EP claimed
EP-0435635-A2 Electrically conductive layer for electrical devices XEROX CORPORATION (US) 1991-07-03 EP claimed
EP-0435635-B1 Electrically conductive layer for electrical devices XEROX CORP (US) 1996-09-18 EP disclosed
EP-0435633-B1 Electrically conductive layer for electrical devices XEROX CORP (US) 1996-09-11 EP disclosed
US-5466551-A Image member including a grounding layer XEROX CORPORATION (US) 1995-11-14 US disclosed
US-5214094-A High solids, coatable viscosity; chain transfer solvent in delayed reactant mixture; storage stable H. & N. CHEMICAL COMPANY (US) 1993-05-25 US disclosed
US-5063128-A Forming a semitransparent conductive layer of particles having acidic surfaces and a polymer; xerography; humidity resistance; durability XEROX CORPORATION (US) 1991-11-05 US disclosed
US-5063125-A For electrographic imaging XEROX CORPORATION (US) 1991-11-05 US disclosed
EP-0435633-A2 Electrically conductive layer for electrical devices XEROX CORPORATION (US) 1991-07-03 EP disclosed
EP-0435635-A2 Electrically conductive layer for electrical devices XEROX CORPORATION (US) 1991-07-03 EP disclosed