⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL378795 | 0.81 | — | — | |
| SCHEMBL19350346 | 0.81 | — | — | |
| SCHEMBL4511226 | 0.78 | — | — | |
| SCHEMBL1012929 | 0.74 | — | — | |
| SCHEMBL4844560 | 0.72 | — | — | |
| SCHEMBL3451050 | 0.72 | — | — | |
| SCHEMBL3994333 | 0.72 | — | — | |
| SCHEMBL7780148 | 0.72 | — | — | |
| SCHEMBL4502786 | 0.70 | — | — | |
| SCHEMBL13373451 | 0.69 | PKM (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12018021-B2 | Thiophene derivatives for the treatment of disorders caused by IgE | UCB Biopharma SRL (BE) | 2024-06-25 | — | — | US | disclosed |
| CN-118164990-A | Method for synthesizing pyrazolo [1,5-a ] [1,3,5] triazine derivative intermediate by boron trifluoride catalysis under microwave radiation | 陕西师范大学 | 2024-06-11 | — | — | CN | disclosed |
| US-20220332709-A1 | Thiophene derivatives for the treatment of disorders caused by IgE | UCB Biopharma SRL (BE) | 2022-10-20 | — | — | US | disclosed |
| US-20090233960-A1 | Kinase Inhibitors | DEVGEN NV (BE) | 2009-09-17 | — | — | US | disclosed |
| EP-1934181-A2 | KINASE INHIBITORS | Devgen NV (BE) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007042321-A2 | KINASE INHIBITORS | DEVGEN N.V. (BE) | 2007-04-19 | — | — | WO | disclosed |