Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15614503 | 0.86 | ADORA2A (0.50) | ADORA2AADORA3ADORA1NPC1RAB9A | |
| SCHEMBL4499552 | 0.85 | ADORA2A (0.49) | ADORA2AADORA3ADORA1NPC1RAB9A | |
| SCHEMBL982676 | 0.81 | KMT2A (0.57) | ADORA2AADORA3ADORA1NPC1RAB9A | |
| SCHEMBL2516609 | 0.79 | ADORA2A (0.55) | ADORA2AADORA3ADORA1NPC1RAB9A | |
| SCHEMBL1459312 | 0.79 | ADORA2A (0.55) | ADORA2AADORA3ADORA1NPC1RAB9A | |
| SCHEMBL16244646 | 0.79 | KDM4E (0.50) | ADORA2AADORA3ADORA1NPC1RAB9A | |
| SCHEMBL5697375 | 0.78 | ADORA3 (0.36) | ADORA2AADORA3ADORA1NPC1RAB9A | |
| SCHEMBL3676305 | 0.78 | ADORA2A (0.54) | ADORA2AADORA3ADORA1NPC1RAB9A | |
| SCHEMBL4515409 | 0.77 | BAZ2B (0.46) | ADORA2AADORA3ADORA1NPC1RAB9A | |
| SCHEMBL28553124 | 0.77 | BAZ2B (0.46) | ADORA2AADORA3ADORA1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7501527-B2 | Method for the production of fluoromethyl-substituted heterocycles | BAYER CROPSCIENCE GMBH (DE) | 2009-03-10 | — | — | US | disclosed |
| US-20060276656-A1 | Method for the production of fluoromethyl-substituted heterocycles | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276656-A1 | Method for the production of fluoromethyl-substituted heterocycles | FLI1, CBR3, CBR1 | ADORA2A 1777/4885ADORA3 1563/4885ADORA1 2315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.