Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.80 |
| ▸ | MAOB | P27338 | 4/20 | 0.52 |
| ▸ | MAOA | P21397 | 3/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | CD44 | P16070 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | DRD5 | P21918 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | BAD | Q92934 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29354295 | 0.96 | — | — | |
| SCHEMBL9662 | 0.96 | — | — | |
| SCHEMBL451157 | 0.96 | TSHR (0.86) | TSHRMAOBMAOACYP2A6HTR2C | |
| SCHEMBL3057782 | 0.96 | TSHR (0.86) | TSHRMAOBMAOACYP2A6HTR2C | |
| Hydrochloric Acid SCHEMBL11437718 | 0.93 | TSHR (0.80) | TSHRMAOBMAOACYP2A6HTR2C | |
| Ammonia Solution, Strong SCHEMBL6332955 | 0.93 | TSHR (0.80) | TSHRMAOBMAOACYP2A6HTR2C | |
| Methane SCHEMBL19946467 | 0.93 | TSHR (0.80) | TSHRMAOBMAOACYP2A6HTR2C | |
| Fluoride SCHEMBL9776698 | 0.93 | TSHR (0.80) | TSHRMAOBMAOACYP2A6HTR2C | |
| SCHEMBL8676208 | 0.93 | TSHR (0.80) | TSHRMAOBMAOACYP2A6HTR2C | |
| Water SCHEMBL7121211 | 0.93 | TSHR (0.80) | TSHRMAOBMAOACYP2A6HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6858610-B2 | Potassium channel inhibitors | ICAGEN, INC. (US) | 2005-02-22 | — | — | US | disclosed |
| US-6849634-B2 | Potassium channel inhibitors | ICAGEN (US) | 2005-02-01 | — | — | US | disclosed |
| EP-1345905-A1 | POTASSIUM CHANNEL INHIBITORS | Icagen, Inc. (US) | 2003-09-24 | — | — | EP | disclosed |
| US-20030013706-A1 | Potassium channel inhibitors | ICAGEN | 2003-01-16 | — | — | US | disclosed |
| US-20020161011-A1 | Potassium channel inhibitors | ICAGEN | 2002-10-31 | — | — | US | disclosed |
| US-6458794-B2 | ANTIARRHYTHMIA AGENT, ANTIPROLIFERATIVE AGENT | ICAGEN, INC. | 2002-10-01 | — | — | US | disclosed |
| EP-1240147-A1 | POTASSIUM CHANNEL INHIBITORS | Icagen, Inc. (US) | 2002-09-18 | — | — | EP | disclosed |
| WO-2002060874-A1 | POTASSIUM CHANNEL INHIBITORS | ICAGEN INCORPORATED (US) | 2002-08-08 | — | — | WO | disclosed |
| US-20020006929-A1 | Potassium channel inhibitors | ICAGEN, INC. | 2002-01-17 | — | — | US | disclosed |
| WO-2001046155-A1 | POTASSIUM CHANNEL INHIBITORS | ICAGEN, INC. (US) | 2001-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020161011-A1 | Potassium channel inhibitors | KCNN2, KCNN1, KCNN3 | TSHR 3128/4885MAOB 3647/4885MAOA 4135/4885 |
| US-20020006929-A1 | Potassium channel inhibitors | KCNN2, KCNN1, KCNN3 | TSHR 3128/4885MAOB 3647/4885MAOA 4135/4885 |
| US-20030013706-A1 | Potassium channel inhibitors | KCNN2, KCNN1, KCNN3 | TSHR 3128/4885MAOB 3647/4885MAOA 4135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.