Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 9/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.33 |
| ▸ | TACR1 | P25103 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4501835 | 0.84 | CETP (0.50) | CETP | |
| SCHEMBL170412 | 0.84 | CYP1A2 (0.41) | CETPCYP1A2METAP2 | |
| SCHEMBL4501452 | 0.83 | NR3C1 (0.35) | CETPPIK3CDTACR1 | |
| SCHEMBL4499332 | 0.82 | NR3C1 (0.34) | CETPPIK3CDTACR1 | |
| SCHEMBL4510002 | 0.81 | NR3C1 (0.37) | CETPPIK3CDTACR1 | |
| SCHEMBL12051888 | 0.77 | CETP (0.36) | CETP | |
| SCHEMBL4499835 | 0.76 | CETP (0.51) | CETPPIK3CD | |
| SCHEMBL4505763 | 0.74 | CETP (0.51) | CETP | |
| SCHEMBL4509476 | 0.71 | CETP (0.49) | CETP | |
| SCHEMBL4501390 | 0.71 | CETP (0.58) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090023729-A1 | Trisubstituted amine compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023729-A1 | Trisubstituted amine compound | CETP, MTTP, APOB | CETP 1/4885CYP1A2 650/4885METAP2 132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.