Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ACKR3 | P25106 | 5/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4027919 | 0.80 | KDM4E (0.61) | KDM4EALOX15TSHRTDP1L3MBTL1 | |
| SCHEMBL4030636 | 0.77 | FFAR1 (0.53) | L3MBTL1PPARGRAB9ASMN1; SMN2GAA | |
| SCHEMBL6555825 | 0.77 | PPARA (0.61) | KDM4EALOX15TSHRTDP1L3MBTL1 | |
| SCHEMBL4026210 | 0.76 | RAB9A (0.59) | TSHRNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6555798 | 0.75 | KDM4E (0.59) | KDM4EALOX15TSHRTDP1L3MBTL1 | |
| SCHEMBL4025386 | 0.75 | RAB9A (0.58) | TSHRNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL29571968 | 0.74 | KDM4E (0.74) | KDM4EALOX15TSHRTDP1L3MBTL1 | |
| SCHEMBL5935612 | 0.74 | KDM4E (0.74) | KDM4EALOX15TSHRTDP1L3MBTL1 | |
| SCHEMBL6555876 | 0.74 | KDM4E (0.58) | KDM4EALOX15TSHRTDP1L3MBTL1 | |
| SCHEMBL6556023 | 0.74 | TSHR (0.50) | KDM4EALOX15TSHRTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275565-A1 | Substituted aralkyl derivatives | CADILA HEALTHCARE LIMITED (IN) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275565-A1 | Substituted aralkyl derivatives | UGT1A7, UGT1A10, UGT2B7 | KDM4E 4614/4885ALOX15 1929/4885TSHR 3987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.