Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A2 | O95436 | 12/20 | 0.45 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.45 |
| ▸ | SLC34A3 | Q8N130 | 1/20 | 0.45 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ADCYAP1R1 | P41586 | 2/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45121 | 1.00 | SLC34A2 (0.45) | SLC34A2SLC34A1SLC34A3SLC20A1RAB9A | |
| SCHEMBL266360 | 0.91 | SLC34A2 (0.46) | SLC34A2SLC34A1SLC34A3SLC20A1HPGD | |
| SCHEMBL266361 | 0.91 | SLC34A2 (0.46) | SLC34A2SLC34A1SLC34A3SLC20A1HPGD | |
| SCHEMBL41388 | 0.91 | SLC34A2 (0.46) | SLC34A2SLC34A1SLC34A3SLC20A1HPGD | |
| SCHEMBL46618 | 0.90 | SLC34A2 (0.42) | SLC34A2SLC34A1SLC34A3SLC20A1HPGD | |
| SCHEMBL274017 | 0.90 | SLC34A2 (0.49) | SLC34A2SLC34A1SLC34A3SLC20A1HPGD | |
| SCHEMBL267363 | 0.90 | SLC34A2 (0.49) | SLC34A2SLC34A1SLC34A3SLC20A1HPGD | |
| SCHEMBL267364 | 0.90 | SLC34A2 (0.49) | SLC34A2SLC34A1SLC34A3SLC20A1HPGD | |
| SCHEMBL45028 | 0.89 | SLC34A2 (0.43) | SLC34A2SLC34A1SLC34A3SLC20A1RAB9A | |
| SCHEMBL45029 | 0.89 | SLC34A2 (0.43) | SLC34A2SLC34A1SLC34A3SLC20A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2591354-B1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX INC (US) | 2016-09-07 | — | — | EP | disclosed |
| US-20140023611-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. | 2014-01-23 | — | — | US | disclosed |
| EP-2591354-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | Ardelyx, Inc. (US) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012006475-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. (US) | 2012-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140023611-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | SLC10A2, SLC34A2, SLC34A3 | SLC34A2 2/4885SLC34A1 4/4885SLC34A3 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.