Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.54 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.47 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.47 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.47 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4503995 | 1.00 | APOBEC3A (0.54) | APOBEC3AAPOBEC3GALDH1A1KDM4EPLAAT3 | |
| SCHEMBL4894679 | 0.89 | APOBEC3A (0.55) | APOBEC3AAPOBEC3GALDH1A1KDM4EPLAAT3 | |
| SCHEMBL4504502 | 0.89 | APOBEC3A (0.55) | APOBEC3AAPOBEC3GALDH1A1KDM4EPLAAT3 | |
| SCHEMBL4491589 | 0.88 | LMNA (0.49) | APOBEC3AAPOBEC3GALDH1A1KDM4EPLAAT3 | |
| SCHEMBL4889438 | 0.88 | LMNA (0.49) | APOBEC3AAPOBEC3GALDH1A1KDM4EPLAAT3 | |
| SCHEMBL4504871 | 0.88 | ALDH1A1 (0.45) | APOBEC3AAPOBEC3GALDH1A1KDM4EPLAAT3 | |
| SCHEMBL4899711 | 0.88 | ALDH1A1 (0.45) | APOBEC3AAPOBEC3GALDH1A1KDM4EPLAAT3 | |
| SCHEMBL4899806 | 0.85 | EGFR (0.50) | ALDH1A1KDM4EPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL4488945 | 0.85 | EGFR (0.50) | ALDH1A1KDM4EPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL4493878 | 0.83 | ALDH1A1 (0.63) | ALDH1A1KDM4EPLAAT3PLAAT5PLAAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7494989-B2 | Pyridine compounds useful as N-type calcium channel antagonists | AJINOMOTO CO., INC. (JP) | 2009-02-24 | — | — | US | disclosed |
| US-20080070903-A1 | NEW PYRIMIDINE DERIVATIVES AND NEW PYRIDINE DERIVATIVES | AJINOMOTO CO., INC (JP) | 2008-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070903-A1 | NEW PYRIMIDINE DERIVATIVES AND NEW PYRIDINE DERIVATIVES | P2RY10, CACNA1B, CACNA1E | APOBEC3A 3217/4885APOBEC3G 3695/4885ALDH1A1 2263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.