Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.57 |
| ▸ | HTR7 | P34969 | 2/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4512797 | 0.94 | ALDH1A1 (0.59) | ALDH1A1KDM4ESMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL4506995 | 0.92 | ALDH1A1 (0.59) | ALDH1A1KDM4EHTR7HTR1ADRD2 | |
| SCHEMBL4523590 | 0.91 | ALDH1A1 (0.56) | ALDH1A1KDM4EHTR7HTR1ADRD2 | |
| SCHEMBL4518772 | 0.89 | KDM4E (0.57) | ALDH1A1KDM4EHTR7HTR1ADRD2 | |
| SCHEMBL9342470 | 0.87 | KDM4E (0.60) | ALDH1A1KDM4EHTR7HTR1ADRD2 | |
| SCHEMBL4517151 | 0.87 | ALDH1A1 (0.63) | ALDH1A1KDM4ESMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL4515067 | 0.86 | ALDH1A1 (0.59) | ALDH1A1KDM4EHTR7HTR1ADRD2 | |
| SCHEMBL4521072 | 0.86 | ALDH1A1 (0.62) | ALDH1A1KDM4ESMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL4514567 | 0.85 | KDM4E (0.59) | ALDH1A1KDM4EHTR7HTR1ADRD2 | |
| SCHEMBL20794235 | 0.85 | BCHE (0.68) | ALDH1A1KDM4EHTR7HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090258883-A1 | 1H-Indole-Pyridinecarboxamide and 1H-Indole-Piperidinecarboxamide Compounds | LES LABORATOIRES SERVIER (FR) | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258883-A1 | 1H-Indole-Pyridinecarboxamide and 1H-Indole-Piperidinecarboxamide Compounds | IDO1, AHR, IDO2 | ALDH1A1 370/4885KDM4E 2039/4885HTR7 194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.