Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31468266 | 1.00 | CA2 (0.39) | CA2EPHX2TSHRALDH1A1NAMPT | |
| SCHEMBL31468267 | 1.00 | CA2 (0.39) | CA2EPHX2TSHRALDH1A1NAMPT | |
| SCHEMBL31468271 | 1.00 | CA2 (0.39) | CA2EPHX2TSHRALDH1A1NAMPT | |
| SCHEMBL232929 | 1.00 | CA2 (0.39) | CA2EPHX2TSHRALDH1A1NAMPT | |
| SCHEMBL5556018 | 1.00 | CA2 (0.39) | CA2EPHX2TSHRALDH1A1NAMPT | |
| SCHEMBL23451307 | 1.00 | CA2 (0.39) | CA2EPHX2TSHRALDH1A1NAMPT | |
| SCHEMBL31468286 | 1.00 | CA2 (0.39) | CA2EPHX2TSHRALDH1A1NAMPT | |
| SCHEMBL221314 | 0.98 | — | — | |
| SCHEMBL11571033 | 0.94 | EPHX2 (0.37) | CA2EPHX2TSHRALDH1A1NAMPT | |
| SCHEMBL871278 | 0.87 | MEN1 (0.35) | TSHRALDH1A1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3678700-B1 | COMPOUNDS FOR REDUCING THE VISCOSITY OF BIOLOGICAL FORMULATIONS | MERCK SHARP & DOHME LLC (US) | 2024-06-19 | — | — | EP | disclosed |
| US-20220378916-A1 | COMPOUNDS FOR REDUCING THE VISCOSITY OF BIOLOGICAL FORMULATIONS | MERCK SHARP & DOHME LLC (US) | 2022-12-01 | — | — | US | disclosed |
| EP-3678700-A1 | COMPOUNDS FOR REDUCING THE VISCOSITY OF BIOLOGICAL FORMULATIONS | Merck Sharp & Dohme Corp. (US) | 2020-07-15 | — | — | EP | disclosed |
| US-20200206350-A1 | COMPOUNDS FOR REDUCING THE VISCOSITY OF BIOLOGICAL FORMULATIONS | MERCK SHARP & DOHME CORP. (US) | 2020-07-02 | — | — | US | disclosed |
| US-20200206350-A1 | COMPOUNDS FOR REDUCING THE VISCOSITY OF BIOLOGICAL FORMULATIONS | MERCK SHARP & DOHME CORP. (US) | 2020-07-02 | — | — | US | disclosed |
| WO-2019050780-A1 | COMPOUNDS FOR REDUCING THE VISCOSITY OF BIOLOGICAL FORMULATIONS | MERCK SHARP & DOHME CORP. (US) | 2019-03-14 | — | — | WO | disclosed |
| WO-2019050780-A1 | COMPOUNDS FOR REDUCING THE VISCOSITY OF BIOLOGICAL FORMULATIONS | MERCK SHARP & DOHME CORP. (US) | 2019-03-14 | — | — | WO | disclosed |
| US-7494714-B2 | Surfaces that resist the adsorption of biological species | PRESIDENT & FELLOWS OF HARVARD COLLEGE (US) | 2009-02-24 | — | — | US | disclosed |
| US-20070264505-A1 | Resistant to the adsorption of proteins, cells and bacteria; have a chemical chain bonded thereon that comprise a terminal group free of a hydrogen bond donor or where a hydrogen bond donor is sufficiently buried | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2007-11-15 | — | — | US | disclosed |
| US-7276286-B2 | Surfaces that resist the adsorption of biological species | PRESIDENT & FELLOWS OF HARVARD COLLEGE (US) | 2007-10-02 | — | — | US | disclosed |
| US-6818203-B2 | COMPLEXES HAVE CRITICAL MICELLE FORMATION CONCENTRATION, HYDRODYNAMIC MICELLE DIAMETER, AND PROTON RELAXIVITY IN PLASMA CONTRAST MEDIA IN MR IMAGING | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-11-16 | — | — | US | disclosed |
| WO-2002006407-A9 | SURFACES THAT RESIST THE ADSORPTION OF BIOLOGICAL SPECIES | HARVARD COLLEGE (US) | 2003-10-23 | — | — | WO | disclosed |
| EP-1301571-A2 | SURFACES THAT RESIST THE ADSORPTION OF BIOLOGICAL SPECIES | President And Fellows of Harvard College (US) | 2003-04-16 | — | — | EP | disclosed |
| US-20020102405-A1 | Surfaces that resist the adsorption of biological species | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-08-01 | — | — | US | disclosed |
| WO-2002006407-A2 | SURFACES THAT RESIST THE ADSORPTION OF BIOLOGICAL SPECIES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2002-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200206350-A1 | COMPOUNDS FOR REDUCING THE VISCOSITY OF BIOLOGICAL FORMULATIONS | CD274, PDCD1, JAK1 | CA2 3724/4885EPHX2 4838/4885TSHR 407/4885 |
| US-20220378916-A1 | COMPOUNDS FOR REDUCING THE VISCOSITY OF BIOLOGICAL FORMULATIONS | CD274, PDCD1, JAK1 | CA2 3636/4885EPHX2 4815/4885TSHR 485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.