SCHEMBL232929

SCHEMBL232929

COCCOCCOCC(=O)Cl

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.39
EPHX2 P34913 2/20 0.33
TSHR P16473 1/20 0.32
ALDH1A1 P00352 1/20 0.32
NAMPT P43490 1/20 0.32
ABCB11 O95342 1/20 0.31
CYP3A4 P08684 1/20 0.31
ADRA2B P18089 1/20 0.31
OPRD1 P41143 1/20 0.31
SCN5A Q14524 1/20 0.31
CES2 O00748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31468266 1.00 CA2 (0.39) CA2EPHX2TSHRALDH1A1NAMPT
SCHEMBL4512963 1.00 CA2 (0.39) CA2EPHX2TSHRALDH1A1NAMPT
SCHEMBL31468267 1.00 CA2 (0.39) CA2EPHX2TSHRALDH1A1NAMPT
SCHEMBL31468271 1.00 CA2 (0.39) CA2EPHX2TSHRALDH1A1NAMPT
SCHEMBL5556018 1.00 CA2 (0.39) CA2EPHX2TSHRALDH1A1NAMPT
SCHEMBL23451307 1.00 CA2 (0.39) CA2EPHX2TSHRALDH1A1NAMPT
SCHEMBL31468286 1.00 CA2 (0.39) CA2EPHX2TSHRALDH1A1NAMPT
SCHEMBL221314 0.98
SCHEMBL11571033 0.94 EPHX2 (0.37) CA2EPHX2TSHRALDH1A1NAMPT
SCHEMBL871278 0.87 MEN1 (0.35) TSHRALDH1A1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112675716-A UIO-66-NH2Method for preparing high-flux defect-free polyamide membrane by using derivative 山东中莱新材料技术有限公司 2021-04-20 CN claimed
EP-3801553-B1 PRODRUGS OF FULVESTRANT KASHIV BIOSCIENCES LLC (US) 2026-03-25 EP disclosed
CN-118027395-B Coating material, preparation method and application thereof, and lithium battery diaphragm 安徽壹石通材料科学研究院有限公司 2025-04-29 CN disclosed
WO-2025064681-A1 COMPOUNDS AND METHODS FOR TREATING BACTERIAL INFECTIONS ENTASIS THERAPEUTICS INC. (US) 2025-03-27 WO disclosed
WO-2024143485-A1 COMPOUND, COMPOSITION, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR 三菱ケミカル株式会社 2024-07-04 WO disclosed
EP-3678700-B1 COMPOUNDS FOR REDUCING THE VISCOSITY OF BIOLOGICAL FORMULATIONS MERCK SHARP & DOHME LLC (US) 2024-06-19 EP disclosed
CN-118027395-A Coating material, preparation method and application thereof, and lithium battery diaphragm 安徽壹石通材料科学研究院有限公司 2024-05-14 CN disclosed
US-20230357145-A1 C4-CARBOXYLIC ACID-SUBSTITUTED TRYPTAMINE DERIVATIVES AND METHODS OF USING Enveric Biosciences Canada Inc. (CA) 2023-11-09 US disclosed
CN-112675716-B UIO-66-NH 2 Method for preparing high-flux defect-free polyamide membrane by using base derivative 山东中莱新材料技术有限公司 2023-05-30 CN disclosed
US-20230010108-A1 A CONJUGATION LINKER CONTAINING 2,3-DIAMINOSUCCINYL GROUP HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-01-12 US disclosed
EP-0344990-B1 Mitomycin derivatives and intermediates therefor KYOWA HAKKO KOGYO KK (JP) 1993-12-15 EP disclosed
US-5254724-A Method for synthesis of desferrioxamine B, analogs and homologs thereof UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 1993-10-19 US disclosed
WO-1993009088-A1 IMPROVED METHOD FOR SYNTHESIS OF DESFERRIOXAMINE B, ANALOGS AND HOMOLOGS THEREOF UNIVERSITY OF FLORIDA (US) 1993-05-13 WO disclosed
US-5021423-A Antibiotic, antitumor agent KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed
EP-0344990-A1 Mitomycin derivatives and intermediates therefor KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) 1989-12-06 EP disclosed
EP-0019745-B1 2-AMINOPROPANAL ACETALS, THEIR PREPARATION, FUNGICIDAL FORMULATIONS CONTAINING THEM, THEIR PREPARATION AND PROCESS FOR COMBATING FUNGI BASF Aktiengesellschaft (DE) 1982-07-28 EP disclosed
EP-0019745-A1 2-Aminopropanal acetals, their preparation, fungicidal formulations containing them, their preparation and process for combating fungi BASF Aktiengesellschaft (DE) 1980-12-10 EP disclosed
US-4152526-A N-acyl derivatives of 3-amino-2,4,6-triiodobenzoic acid CHEMIE LINZ AKTIENGESELLSCHAFT (AT) 1979-05-01 US disclosed
US-4111937-A IODINATED ANILIC ACIDS STERLING DRUG INC. (US) 1978-09-05 US disclosed
US-4031088-A Iodinated anilic acids STERLING DRUG INC. (US) 1977-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357145-A1 C4-CARBOXYLIC ACID-SUBSTITUTED TRYPTAMINE DERIVATIVES AND METHODS OF USING HTR4, HTR2C, CNR2 CA2 1644/4885EPHX2 1011/4885TSHR 1285/4885
US-20230010108-A1 A CONJUGATION LINKER CONTAINING 2,3-DIAMINOSUCCINYL GROUP DAO, DDO, DCLRE1A CA2 690/4885EPHX2 458/4885TSHR 3815/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.