Pyrene

Pyrene

SCHEMBL4513191

OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@H]1O.c1cc2ccc3cccc4ccc(c1)c2c34

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 4/20 0.45
PYGL P06737 2/20 0.43
CD209 Q9NNX6 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrene SCHEMBL4530833 1.00 SLC5A2 (0.45) SLC5A2PYGLCD209
B-D-Galactose SCHEMBL15768434 0.87 PYGL (0.49) SLC5A2PYGLCD209
Dextrose SCHEMBL3220374 0.87 PYGL (0.49) SLC5A2PYGLCD209
Ribose (Furanose) SCHEMBL5139187 0.85 PYGL (0.47) SLC5A2PYGLCD209
Ribose (Furanose) SCHEMBL27934652 0.85 PYGL (0.47) SLC5A2PYGLCD209
Anthracene SCHEMBL4526453 0.84 PYGL (0.50) SLC5A2PYGLCD209
Beta-D-Glucose SCHEMBL27745359 0.80 LGALS1 (0.52) SLC5A2
Dextrose SCHEMBL28143229 0.80 LGALS1 (0.52) SLC5A2
B-D-Galactose SCHEMBL27766291 0.80 LGALS1 (0.52) SLC5A2
B-D-Galactose SCHEMBL28251165 0.80 LGALS1 (0.52) SLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140295403-A1 DETECTION OF BIOLOGICAL MOLECULES BY DIFFERENTIAL PARTITIONING OF ENZYME SUBSTRATES AND PRODUCTS QUEEN'S UNIVERSITY AT KINGSTON (CA) 2014-10-02 US disclosed
US-8632966-B2 Detection of biological molecules by differential partitioning of enzyme substrates and products QUEEN'S UNIVERSITY AT KINGSTON (CA) 2014-01-21 US disclosed
US-20130217041-A1 DETECTION OF BIOLOGICAL MOLECULES BY DIFFERENTIAL PARTITIONING OF ENZYME SUBSTRATES AND PRODUCTS QUEEN'S UNIVERSITY AT KINGSTON (CA) 2013-08-22 US disclosed
US-8377686-B2 Detection of biological molecules by differential partitioning of enzyme substrates and products QUEEN'S UNIVERSITY AT KINGSTON (CA) 2013-02-19 US disclosed
US-20090117600-A1 Detection of biological molecules by differential partitioning of enzyme substrates and products QUEEN'S UNIVERSITY AT KINGSTON (CA) 2009-05-07 US disclosed
US-7402426-B2 Analyzing microorganism associated with an enzyme in a sample water, food, soil, or a biological sample, enzyme-linked immunosorbent assay, automatic detect fluorescence with optical fiber, separate with polydimethylsiloxane films; diagnostic kits QUEEN'S UNIVERSITY AT KINGSTON (CA) 2008-07-22 US disclosed
EP-1539986-B1 DETECTION OF BIOLOGICAL MOLECULES BY DIFFERENTIAL PARTITIONING OF ENZYME SUBSTRATES AND PRODUCTS UNIV KINGSTON (CA) 2007-07-18 EP disclosed
EP-1539986-A1 DETECTION OF BIOLOGICAL MOLECULES BY DIFFERENTIAL PARTITIONING OF ENZYME SUBSTRATES AND PRODUCTS Queen's University at Kingston (CA) 2005-06-15 EP disclosed
US-20040106164-A1 Analyzing microorganism associated with an enzyme in a sample water, food, soil, or a biological sample, enzyme-linked immunosorbent assay, automatic detect fluorescence with optical fiber, separate with polydimethylsiloxane films; diagnostic kits QUEEN'S UNIVERSITY AT KINGSTON (CA) 2004-06-03 US disclosed
WO-2004027084-A1 DETECTION OF BIOLOGICAL MOLECULES BY DIFFERENTIAL PARTITIONING OF ENZYME SUBSTRATES AND PRODUCTS QUEEN'S UNIVERSITY AT KINGSTON (CA) 2004-04-01 WO disclosed