Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KIF11 | P52732 | 3/20 | 0.37 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4513752 | 1.00 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2AKIF11MAP1LC3B | |
| SCHEMBL5362757 | 0.82 | KIF11 (0.55) | ALDH1A1MEN1KMT2AKIF11MAP1LC3B | |
| SCHEMBL5362764 | 0.82 | KIF11 (0.55) | ALDH1A1MEN1KMT2AKIF11MAP1LC3B | |
| SCHEMBL5447775 | 0.82 | KIF11 (0.55) | ALDH1A1MEN1KMT2AKIF11MAP1LC3B | |
| SCHEMBL4531455 | 0.81 | PIK3CD (0.40) | ALDH1A1MEN1KMT2AKIF11MAP1LC3B | |
| SCHEMBL4532582 | 0.69 | KIF11 (0.46) | KIF11MAP1LC3BCYP3A4CYP2C19KCNH2 | |
| SCHEMBL4518757 | 0.67 | KIF11 (0.51) | ALDH1A1MEN1KMT2AKIF11MAP1LC3B | |
| SCHEMBL4518754 | 0.67 | KIF11 (0.51) | ALDH1A1MEN1KMT2AKIF11MAP1LC3B | |
| SCHEMBL6314431 | 0.62 | MEN1 (0.67) | ALDH1A1MEN1KMT2ARXFP1MAPT | |
| SCHEMBL6313235 | 0.60 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2ACYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7528137-B2 | Compounds, compositions, and methods | CYTOKINETICS, INC. (US) | 2009-05-05 | — | — | US | disclosed |