Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20526175 | 1.00 | SMN1; SMN2 (0.69) | SMN1; SMN2LMNAL3MBTL1MAPTIDO1 | |
| SCHEMBL20136946 | 0.98 | SMN1; SMN2 (0.68) | SMN1; SMN2LMNAL3MBTL1MAPTIDO1 | |
| SCHEMBL25030665 | 0.92 | LMNA (0.58) | SMN1; SMN2LMNAL3MBTL1MAPTIDO1 | |
| SCHEMBL25030131 | 0.92 | LMNA (0.62) | SMN1; SMN2LMNAL3MBTL1MAPTIDO1 | |
| SCHEMBL5533423 | 0.91 | LMNA (0.56) | SMN1; SMN2LMNAL3MBTL1MAPTIDO1 | |
| SCHEMBL903459 | 0.91 | LMNA (0.58) | SMN1; SMN2LMNAL3MBTL1MAPTIDO1 | |
| SCHEMBL24572425 | 0.91 | SMN1; SMN2 (0.69) | SMN1; SMN2LMNAL3MBTL1MAPTIDO1 | |
| SCHEMBL18886286 | 0.91 | SMN1; SMN2 (0.69) | SMN1; SMN2LMNAL3MBTL1MAPTIDO1 | |
| SCHEMBL20107353 | 0.91 | LMNA (0.61) | SMN1; SMN2LMNAL3MBTL1MAPTIDO1 | |
| SCHEMBL25029156 | 0.90 | LMNA (0.59) | SMN1; SMN2LMNAL3MBTL1MAPTIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7494714-B2 | Surfaces that resist the adsorption of biological species | PRESIDENT & FELLOWS OF HARVARD COLLEGE (US) | 2009-02-24 | — | — | US | disclosed |
| US-20070264505-A1 | Resistant to the adsorption of proteins, cells and bacteria; have a chemical chain bonded thereon that comprise a terminal group free of a hydrogen bond donor or where a hydrogen bond donor is sufficiently buried | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2007-11-15 | — | — | US | disclosed |
| US-7276286-B2 | Surfaces that resist the adsorption of biological species | PRESIDENT & FELLOWS OF HARVARD COLLEGE (US) | 2007-10-02 | — | — | US | disclosed |
| WO-2002006407-A9 | SURFACES THAT RESIST THE ADSORPTION OF BIOLOGICAL SPECIES | HARVARD COLLEGE (US) | 2003-10-23 | — | — | WO | disclosed |
| EP-1301571-A2 | SURFACES THAT RESIST THE ADSORPTION OF BIOLOGICAL SPECIES | President And Fellows of Harvard College (US) | 2003-04-16 | — | — | EP | disclosed |
| US-20020102405-A1 | Surfaces that resist the adsorption of biological species | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-08-01 | — | — | US | disclosed |
| WO-2002006407-A2 | SURFACES THAT RESIST THE ADSORPTION OF BIOLOGICAL SPECIES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2002-01-24 | — | — | WO | disclosed |