Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TGM2 | P21980 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | TLR2 | O60603 | 1/20 | 0.45 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | KLK7 | P49862 | 1/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL903459 | 0.93 | LMNA (0.58) | LMNASMN1; SMN2TGM2MAPTHTT | |
| SCHEMBL20526175 | 0.91 | SMN1; SMN2 (0.69) | LMNASMN1; SMN2TGM2MAPTHTT | |
| SCHEMBL4513964 | 0.91 | SMN1; SMN2 (0.69) | LMNASMN1; SMN2TGM2MAPTHTT | |
| SCHEMBL20136946 | 0.89 | SMN1; SMN2 (0.68) | LMNASMN1; SMN2TGM2MAPTHTT | |
| SCHEMBL25030418 | 0.85 | LMNA (0.60) | LMNASMN1; SMN2TGM2MAPTHTT | |
| SCHEMBL5530584 | 0.85 | LMNA (0.66) | LMNASMN1; SMN2TGM2MAPTHTT | |
| SCHEMBL25028582 | 0.84 | LMNA (0.59) | LMNASMN1; SMN2TGM2MAPTHTT | |
| SCHEMBL21106167 | 0.84 | L3MBTL1 (0.56) | LMNASMN1; SMN2MAPTL3MBTL1SYK | |
| SCHEMBL3052852 | 0.84 | HTT (0.61) | LMNASMN1; SMN2TGM2MAPTHTT | |
| SCHEMBL9667908 | 0.84 | HTT (0.61) | LMNASMN1; SMN2TGM2MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7202227-B2 | Multifunctional molecular complexes for gene transfer to cells | WYETH (US) | 2007-04-10 | — | — | US | disclosed |
| US-20050239204-A1 | Multifunctional molecular complexes for gene transfer to cells | WYETH (US) | 2005-10-27 | — | — | US | disclosed |
| EP-0789708-B1 | MULTIFUNCTIONAL MOLECULAR COMPLEXES FOR GENE TRANSFER TO CELLS | WYETH CORP (US) | 2004-11-03 | — | — | EP | disclosed |
| US-20040214328-A9 | Multifunctional molecular complexes for gene transfer to cells | AMERICAN HOME PRODUCTS CORPORATION (US) | 2004-10-28 | — | — | US | disclosed |
| US-20020155607-A1 | Multifunctional molecular complexes for gene transfer to cells | AMERICAN HOME PRODUCTS CORPORATION (US) | 2002-10-24 | — | — | US | disclosed |
| US-6379965-B1 | NUCLEIC ACID NONCOVALENTLY ASSOCIATED WITH A POLYAMINE COMPOUND THAT IS COVALENTLY ATTACHED TO AN ENDOSOME DISRUPTING AGENT SUCH AS CHOLIC ACID; NONVIRAL VECTORS | AMERICAN HOME PRODUCTS CORPORATION | 2002-04-30 | — | — | US | disclosed |
| US-6127170-A | GENE THERAPY | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-10-03 | — | — | US | disclosed |
| EP-0789708-A4 | MULTIFUNCTIONAL MOLECULAR COMPLEXES FOR GENE TRANSFER TO CELLS | APOLLON INC (US) | 1999-12-29 | — | — | EP | disclosed |
| EP-0789708-A1 | MULTIFUNCTIONAL MOLECULAR COMPLEXES FOR GENE TRANSFER TO CELLS | APOLLON, INC. (US) | 1997-08-20 | — | — | EP | disclosed |
| WO-1996010038-A1 | MULTIFUNCTIONAL MOLECULAR COMPLEXES FOR GENE TRANSFER TO CELLS | APOLLON, INC. (US) | 1996-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040214328-A9 | Multifunctional molecular complexes for gene transfer to cells | SNRPE, TARBP1, HNRNPH3 | LMNA 1077/4885SMN1; SMN2 2469/4885TGM2 2069/4885 |
| US-20020155607-A1 | Multifunctional molecular complexes for gene transfer to cells | SNRPE, TARBP1, HNRNPH3 | LMNA 1077/4885SMN1; SMN2 2469/4885TGM2 2069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.