Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4507999 | 0.90 | GPR119 (0.53) | GPR119SMN1; SMN2NAMPTNPC1LMNA | |
| SCHEMBL4518794 | 0.89 | GPR119 (0.51) | GPR119SMN1; SMN2NAMPTNPC1LMNA | |
| SCHEMBL4516443 | 0.89 | GPR119 (0.51) | GPR119SMN1; SMN2NAMPTNPC1LMNA | |
| SCHEMBL13757761 | 0.89 | MAPT (0.54) | GPR119SMN1; SMN2NAMPTNPC1LMNA | |
| SCHEMBL13757744 | 0.88 | GPR119 (0.55) | GPR119SMN1; SMN2NAMPTNPC1LMNA | |
| SCHEMBL4518131 | 0.87 | PTPN2 (0.62) | GPR119SMN1; SMN2NAMPTNPC1LMNA | |
| SCHEMBL13757759 | 0.85 | GPR119 (0.52) | GPR119SMN1; SMN2NAMPTNPC1LMNA | |
| SCHEMBL4515218 | 0.85 | GPR119 (0.48) | GPR119SMN1; SMN2NAMPTNPC1LMNA | |
| SCHEMBL13757766 | 0.84 | PTPN2 (0.58) | GPR119SMN1; SMN2NAMPTNPC1LMNA | |
| SCHEMBL7366692 | 0.84 | GPR119 (0.59) | GPR119NAMPTLMNATGFBR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203676-A1 | G-protein Coupled Receptor Agonists | PROSIDION LIMITED (GB) | 2009-08-13 | — | — | US | disclosed |
| US-20090203676-A1 | G-protein Coupled Receptor Agonists | PROSIDION LIMITED (GB) | 2009-08-13 | — | — | US | disclosed |
| US-20090203676-A1 | G-protein Coupled Receptor Agonists | PROSIDION LIMITED (GB) | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203676-A1 | G-protein Coupled Receptor Agonists | GPR119, GCGR, GPBAR1 | GPR119 1/4885SMN1; SMN2 3393/4885NAMPT 3068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.