Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TCF4 | P15884 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4505639 | 0.93 | DRD4 (0.44) | DRD4SMN1; SMN2MAPTLMNARAB9A | |
| Trifluoroacetic Acid SCHEMBL4499863 | 0.92 | SMN1; SMN2 (0.44) | DRD4SMN1; SMN2MAPTLMNARAB9A | |
| Trifluoroacetic Acid SCHEMBL4510281 | 0.91 | SMN1; SMN2 (0.44) | DRD4SMN1; SMN2MAPTLMNARAB9A | |
| Hydrochloric Acid SCHEMBL4505071 | 0.91 | DRD4 (0.46) | DRD4SMN1; SMN2MAPTLMNARAB9A | |
| Trifluoroacetic Acid SCHEMBL4512342 | 0.90 | DRD4 (0.51) | DRD4SMN1; SMN2MAPTLMNARAB9A | |
| Trifluoroacetic Acid SCHEMBL4507493 | 0.89 | SMN1; SMN2 (0.43) | DRD4SMN1; SMN2MAPTLMNARAB9A | |
| Trifluoroacetic Acid SCHEMBL4503307 | 0.89 | SMN1; SMN2 (0.44) | DRD4SMN1; SMN2MAPTLMNARAB9A | |
| Hydrochloric Acid SCHEMBL4513041 | 0.89 | DRD4 (0.44) | DRD4SMN1; SMN2MAPTLMNARAB9A | |
| Trifluoroacetic Acid SCHEMBL4504826 | 0.89 | DRD4 (0.44) | DRD4SMN1; SMN2MAPTLMNARAB9A | |
| Trifluoroacetic Acid SCHEMBL4505611 | 0.89 | DRD4 (0.44) | DRD4SMN1; SMN2MAPTLMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | SCD, SCD5, SMS | DRD4 2674/4885SMN1; SMN2 2075/4885MAPT 4022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.