Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | PARL | Q9H300 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL776677 | 0.87 | CA2 (0.61) | TDP1CA2CA9CA1TSHR | |
| SCHEMBL11414929 | 0.87 | CA2 (0.55) | TDP1CA2CA9CA1MAPT | |
| SCHEMBL7286478 | 0.85 | CA2 (0.59) | TDP1CA2CA9CA1TSHR | |
| SCHEMBL17737231 | 0.83 | NPC1 (0.55) | LMNASMN1; SMN2TDP1CA2CA9 | |
| SCHEMBL28268031 | 0.81 | KMT2A (0.48) | LMNATDP1CA2CA9CA1 | |
| SCHEMBL4510112 | 0.81 | NAMPT (0.52) | LMNATDP1CA2CA9CA1 | |
| SCHEMBL776873 | 0.79 | CA2 (0.47) | CA2CA9CA1PARLPKM | |
| SCHEMBL20428070 | 0.77 | TSHR (0.55) | LMNASMN1; SMN2CA2CA9CA1 | |
| SCHEMBL7183273 | 0.76 | CA1 (0.53) | LMNACA2CA9CA1TSHR | |
| SCHEMBL27772414 | 0.76 | HTT (0.51) | LMNASMN1; SMN2TDP1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403456-A | Method for synthesizing Edwardsienta intermediate 3-hydroxy-4-methoxyphenylpropanal | 成都大学 | 2022-11-29 | — | — | CN | disclosed |
| CN-113354577-B | Monocarbonyl curcuminoid compound and preparation method and application thereof | 西南医科大学附属中医医院 | 2022-08-26 | — | — | CN | disclosed |
| US-7612097-B2 | Method for producing bactericidal pyridine compound and bactericidal pyridine compound | TAMA KAGAKU KOGYO CO., LTD. (JP) | 2009-11-03 | — | — | US | disclosed |
| US-20070099961-A1 | Method for producing bactericidal pyridine compound and bactericidal pyridine compound | Kourai, Hiroki (JP) | 2007-05-03 | — | — | US | disclosed |
| EP-1683787-A1 | METHOD FOR PRODUCING BACTERICIDAL PYRIDINE COMPOUND AND BACTERICIDAL PYRIDINE COMPOUND | Tama Kagaku Kogyo Co., Ltd. (JP) | 2006-07-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099961-A1 | Method for producing bactericidal pyridine compound and bactericidal pyridine compound | BLVRB, CBR3, TLR7 | LMNA 4717/4885SMN1; SMN2 4476/4885TDP1 4728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.