Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 8/20 | 0.58 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4529142 | 0.78 | GRM5 (0.47) | GRM5 | |
| SCHEMBL4528127 | 0.76 | GRM5 (0.58) | GRM5 | |
| SCHEMBL18706643 | 0.75 | ALDH1A1 (0.59) | GRM5NFE2L2KEAP1 | |
| SCHEMBL18706645 | 0.75 | ALDH1A1 (0.59) | GRM5NFE2L2KEAP1 | |
| SCHEMBL990982 | 0.74 | GRM5 (0.98) | GRM5HCRTR1 | |
| SCHEMBL990799 | 0.73 | GRM5 (1.00) | GRM5HCRTR1 | |
| SCHEMBL992091 | 0.73 | GRM5 (1.00) | GRM5HCRTR1 | |
| SCHEMBL990800 | 0.73 | GRM5 (1.00) | GRM5HCRTR1 | |
| SCHEMBL5909114 | 0.73 | GRM5 (0.66) | GRM5 | |
| SCHEMBL4530472 | 0.71 | GABRA5 (0.39) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090005363-A1 | Organic Compounds | NOVARTIS AG (CH) | 2009-01-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005363-A1 | Organic Compounds | NNT, NAPRT, CHRNA5 | GRM5 680/4885NFE2L2 3769/4885KEAP1 3536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.