Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.45 |
| ▸ | MAOA | P21397 | 4/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11038152 | 0.98 | TAAR1 (0.58) | TAAR1SLC6A2SMN1; SMN2CYP2A6HTR2A | |
| Hydrochloric Acid SCHEMBL11164072 | 0.98 | TAAR1 (0.58) | TAAR1SLC6A2SMN1; SMN2CYP2A6HTR2A | |
| Water SCHEMBL2959270 | 0.98 | TAAR1 (0.58) | TAAR1SLC6A2SMN1; SMN2CYP2A6HTR2A | |
| Pivalate SCHEMBL5675687 | 0.88 | GRM2 (0.50) | TAAR1SLC6A2SMN1; SMN2ALDH1A1ALOX12 | |
| SCHEMBL21058265 | 0.87 | SLC6A2 (0.44) | TAAR1SLC6A2CYP2A6HTR2ACYP1A2 | |
| SCHEMBL21058273 | 0.87 | TAAR1 (0.48) | TAAR1SLC6A2MAOAMAOBLMNA | |
| SCHEMBL3797223 | 0.86 | TAAR1 (0.56) | TAAR1SLC6A2SMN1; SMN2CYP2A6HTR2A | |
| SCHEMBL21058237 | 0.86 | TAAR1 (0.54) | TAAR1SLC6A2SMN1; SMN2CYP2A6HTR2A | |
| Bromide SCHEMBL11133528 | 0.85 | SLC6A2 (0.54) | TAAR1SLC6A2HTR2AAOC3MAOA | |
| SCHEMBL3802516 | 0.85 | MAOA (0.54) | TAAR1SLC6A2HTR2AAOC3MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 349 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4399234-A1 | PRODUCTION OF A BLOCKED CURING AGENT BASED ON A PARTLY ORGANIC-BASED POLYISOCYANATE AND USE AS A 1K PUR BAKING ENAMEL | Covestro Deutschland AG (DE) | 2024-07-17 | — | — | EP | claimed |
| WO-2023036861-A1 | PRODUCTION OF A BLOCKED CURING AGENT BASED ON A PARTLY ORGANIC-BASED POLYISOCYANATE AND USE AS A 1K PUR BAKING ENAMEL | COVESTRO DEUTSCHLAND AG (DE) | 2023-03-16 | — | — | WO | claimed |
| EP-4148077-A1 | PRODUCTION OF A BLOCKED CURING AGENT BASED ON A PARTIALLY BIO-BASED POLYISOCYANATE AND USE AS A 1K-PURE STOVING ENAMEL | Covestro Deutschland AG (DE) | 2023-03-15 | — | — | EP | claimed |
| CN-112300149-A | Preparation method of arotinolol hydrochloride | 北京弘德信医药科技有限公司 | 2021-02-02 | — | — | CN | claimed |
| US-10865163-B2 | Carbon dioxide as a directing group for C—H functionalization reactions involving Lewis basic amines, alcohols, thiols, and phosphines for the synthesis of compounds | THE UNIVERSITY OF TOLEDO (US) | 2020-12-15 | — | — | US | claimed |
| US-20200223974-A1 | METHODS AND COMPOSITIONS FOR POLYURETHANE DISPERSIONS USING CAPROLACTAM-DERIVED SOLVENTS | TRUIST BANK, AS ADMINISTRATIVE AGENT | 2020-07-16 | — | — | US | claimed |
| CN-106631831-B | A kind of preparation method of left-handed Terbutaline | 北京盈科瑞创新医药股份有限公司 | 2019-09-20 | — | — | CN | claimed |
| US-20190185392-A1 | Carbon Dioxide as a Directing Group for C-H Functionalization Reactions Involving Lewis Basic Amines, Alcohols, Thiols, and Phosphines for the Synthesis of Compounds | THE UNIVERSITY OF TOLEDO (US) | 2019-06-20 | — | — | US | claimed |
| CN-108623486-A | A kind of preparation method of V hydrochloride of salbutamol intermediate | 重庆康刻尔制药有限公司 | 2018-10-09 | — | — | CN | claimed |
| CN-104557572-B | Levalbuterol intermediate and levalbuterol hydrochloride synthesis method | 上海默学医药科技有限公司 | 2017-02-22 | — | — | CN | claimed |
| US-20070129488-A1 | Preparation of a polyurethane dispersion with blocked isocyanate groups | BAYER MATERIALSCIENCE AG | 2007-06-07 | — | — | US | claimed |
| US-20070123644-A1 | ORGANOSILICON COMPOUNDS WITH A MASKED ISOCYANATE GROUP | WACKER CHEMIE AG (DE) | 2007-05-31 | — | — | US | claimed |
| US-20070072989-A1 | Two-part sizing composition for reinforcement fibers | OWENS-CORNING FIBERGLAS TECHNOLOGY II, LLC | 2007-03-29 | — | — | US | claimed |
| EP-1375551-B1 | Aralkylamine blocking agents for non-aqueous polyisocyanate | BAYER MATERIALSCIENCE AG (DE) | 2006-11-08 | — | — | EP | claimed |
| EP-1229016-B1 | Catalyst and process for the preparation of isocyanate groups containing polyisocyanates with low viscosity and reduced colour | DEGUSSA (DE) | 2006-01-11 | — | — | EP | claimed |
| EP-1375551-A1 | Aralkylamine blocking agents for non-aqueous polyisocyanate | Bayer Aktiengesellschaft (DE) | 2004-01-02 | — | — | EP | claimed |
| EP-1375552-A1 | Aqueous and/or water-reducible polyisocyanates blocked with secondary benzyl amines | Bayer Aktiengesellschaft (DE) | 2004-01-02 | — | — | EP | claimed |
| EP-0844999-B1 | PURIFICATION PROCESS | BIOCHEMIE GMBH (AT) | 2003-04-23 | — | — | EP | claimed |
| CN-1185158-A | Prepn. of clavulanate salts | LEK TOVARNA FARMACEVTSKIH (SI) | 1998-06-17 | — | — | CN | claimed |
| US-3983175-A | FROM ORGANIC HALIDE AND A KETONE | KURARAY CO., LTD. (JA) | 1976-09-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190185392-A1 | Carbon Dioxide as a Directing Group for C-H Functionalization Reactions Involving Lewis Basic Amines, Alcohols, Thiols, and Phosphines for the Synthesis of Compounds | CHKB, HRH3, PNMT | TAAR1 72/4885SLC6A2 859/4885SMN1; SMN2 4609/4885 |
| US-10865163-B2 | Carbon dioxide as a directing group for C—H functionalization reactions involving Lewis basic amines, alcohols, thiols, and phosphines for the synthesis of compounds | CHKB, HRH3, PNMT | TAAR1 86/4885SLC6A2 924/4885SMN1; SMN2 4615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.