Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5609883 | 0.89 | PIN1 (0.58) | HTTPIN1TSHRCRBNIDO1 | |
| SCHEMBL29706163 | 0.84 | HTT (0.54) | HTTALDH1A1PIN1BLMMEN1 | |
| SCHEMBL29484110 | 0.84 | HTT (0.54) | HTTALDH1A1PIN1BLMMEN1 | |
| SCHEMBL2792830 | 0.84 | HTT (0.54) | HTTALDH1A1PIN1BLMMEN1 | |
| SCHEMBL242244 | 0.84 | HTT (0.54) | HTTALDH1A1PIN1BLMMEN1 | |
| SCHEMBL1567657 | 0.84 | IDO1 (0.51) | HTTALDH1A1PIN1BLMMEN1 | |
| SCHEMBL2796237 | 0.84 | HTT (0.54) | HTTALDH1A1PIN1BLMMEN1 | |
| SCHEMBL29608780 | 0.84 | HTT (0.54) | HTTALDH1A1PIN1BLMMEN1 | |
| SCHEMBL2448483 | 0.82 | HTT (0.49) | HTTALDH1A1PIN1BLMMEN1 | |
| Hydrochloric Acid SCHEMBL2999173 | 0.82 | HTT (0.53) | HTTALDH1A1PIN1BLMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4308380-A | 2-Lower alkyl-2 or 3-cephem-4-carboxylic acid derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-12-29 | — | — | US | claimed |
| US-20090233960-A1 | Kinase Inhibitors | DEVGEN NV (BE) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233960-A1 | Kinase Inhibitors | ROCK1, MAP3K1, MAP3K11 | HTT 1131/4885ALDH1A1 2810/4885PIN1 1382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.