SCHEMBL5609883

SCHEMBL5609883

[NH]C(=O)C1CCc2ccccc21

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PIN1 Q13526 5/20 0.58
KCNQ2 O43526 1/20 0.47
IDO1 P14902 2/20 0.43
PDPK1 O15530 1/20 0.43
CRBN Q96SW2 1/20 0.43
ACP3 P15309 1/20 0.43
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
TSHR P16473 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
CYP11B2 P19099 1/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4515757 0.89 HTT (0.49) PIN1IDO1CRBNTSHRHTT
SCHEMBL4830828 0.84 PIN1 (0.62) PIN1KCNQ2IDO1PDPK1CRBN
SCHEMBL12431131 0.82 PIN1 (0.60) PIN1KCNQ2IDO1PDPK1ACP3
SCHEMBL907688 0.82 PIN1 (0.60) PIN1KCNQ2IDO1PDPK1ACP3
SCHEMBL1567245 0.82 PIN1 (0.60) PIN1KCNQ2IDO1PDPK1CRBN
SCHEMBL2790690 0.82 PIN1 (0.60) PIN1KCNQ2IDO1PDPK1ACP3
SCHEMBL1400973 0.82 PIN1 (0.60) PIN1KCNQ2IDO1PDPK1ACP3
SCHEMBL643577 0.81 PIN1 (0.58) PIN1KCNQ2IDO1PDPK1CRBN
SCHEMBL8848989 0.81 PIN1 (0.58) PIN1KCNQ2IDO1PDPK1CRBN
SCHEMBL2475968 0.81 PIN1 (0.58) PIN1KCNQ2IDO1PDPK1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0280275-B1 N-INDANYL CARBOXAMIDE DERIVATIVE AND AGRICULTURAL/HORTICULTURAL FUNGICIDE CONTAINING THE DERIVATIVE AS ACTIVE INGREDIENT MITSUBISHI KASEI CORPORATION (JP) 1992-04-29 EP claimed
US-4308380-A 2-Lower alkyl-2 or 3-cephem-4-carboxylic acid derivatives FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-12-29 US claimed
JP-1313402-A None JP disclosed
JP-2000175-A None JP disclosed
JP-62249966-A None JP disclosed
JP-2157266-A None JP disclosed
JP-10072398-A None JP disclosed
EP-4574815-A1 PROCESS FOR THE SEPARATION OF AROMATIC SULPHONIC ACIDS AND SALTS FROM AQUEOUS PHASES Saltigo GmbH (DE) 2025-06-25 EP disclosed
WO-2014121036-A1 5-DEUTERO-2,4-THIAZOLIDINEDIONE AND 5-DEUTERO-2,4-OXAZOLIDINEDIONE DERIVATIVES AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME DEUTERX, LLC (US) 2014-08-07 WO disclosed
US-20140221369-A1 5-DEUTERO-2,4-THIAZOLIDINEDIONE AND 5-DEUTERO-2,4-OXAZOLIDINEDIONE DERIVATIVES AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME DEUTERX, LLC (US) 2014-08-07 US disclosed
US-7199139-B2 Medicinal compositions containing diuretic and insulin resistance-improving agent SANKYO COMPANY, LIMITED (JP) 2007-04-03 US disclosed
US-6432993-B1 BENZIMIDAZOLE OR IMIDAZO(4,5-B)PYRIDINE DERIVATES; IMMUNOMODULATORS; ALDOSE REDUCTASE AND LIPOXYGENASE INHIBITORS; DIABETES; PREVENTS LIPID PEROXIDATION; ANTILIPEMIC, HYPOTENSIVE AGENTS SANKYO COMPANY, LIMITED (JP) 2002-08-13 US disclosed
EP-1167366-A1 AMINE DERIVATIVES Sankyo Company, Limited (JP) 2002-01-02 EP disclosed
EP-1167357-A1 ALPHA-SUBSTITUTED CARBOXYLIC ACID DERIVATIVES Sankyo Company, Limited (JP) 2002-01-02 EP disclosed
EP-1022272-A1 SUBSTITUTED FUSED HETEROCYCLIC COMPOUNDS Sankyo Company Limited (JP) 2000-07-26 EP disclosed
JP-H1072398-A PRODUCTION OF 1-INDANONE ICHIKAWA GOSEI KAGAKU KK 1998-03-17 JP disclosed
JP-H02157266-A N-INDANYLCARBOXYLIC ACID AMIDE DERIVATIVE AND GERMICIDE FOR AGRICULTURE AND HORTICULTURE CONTAINING THE SAME AS ACTIVE INGREDIENT MITSUBISHI KASEI CORP 1990-06-18 JP disclosed
JP-H02175-A N-INDANYLCARBOXYLIC ACID AMIDE DERIVATIVE AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE CONTAINING THE SAME DERIVATIVE AS ACTIVE COMPONENT MITSUBISHI KASEI CORP 1990-01-05 JP disclosed
JP-H01313402-A CONTROLLER OF GRAY MOLD COMPRISING N-INDANYLCARBOXYLIC ACID AMIDE CATALYST AS ACTIVE INGREDIENT MITSUBISHI KASEI CORP 1989-12-18 JP disclosed
JP-S62249966-A N-INDANYLAMIDE DERIVATIVE AND FUNGICIDE CONTAINING SAME AS ACTIVE INGREDIENT SUMITOMO CHEM CO LTD 1987-10-30 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140221369-A1 5-DEUTERO-2,4-THIAZOLIDINEDIONE AND 5-DEUTERO-2,4-OXAZOLIDINEDIONE DERIVATIVES AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME SRD5A2, PPARD, SRD5A1 PIN1 993/4885KCNQ2 1559/4885IDO1 562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.