SCHEMBL4515779

SCHEMBL4515779

CCCCCCCCCCCCCCCCOC1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.65
LGALS8 O00214 1/20 0.60
LGALS3 P17931 1/20 0.60
LGALS4 P56470 1/20 0.60
CETP P11597 1/20 0.54
GJB2 P29033 1/20 0.52
GBA1 P04062 1/20 0.51
IGF2R P11717 4/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14673220 1.00 MAPK1 (0.65) MAPK1LGALS8LGALS3LGALS4CETP
SCHEMBL2969833 1.00 MAPK1 (0.65) MAPK1LGALS8LGALS3LGALS4CETP
SCHEMBL2446441 1.00 MAPK1 (0.65) MAPK1LGALS8LGALS3LGALS4CETP
SCHEMBL25480871 1.00 MAPK1 (0.65) MAPK1LGALS8LGALS3LGALS4CETP
SCHEMBL17366539 1.00 MAPK1 (0.65) MAPK1LGALS8LGALS3LGALS4CETP
SCHEMBL23016771 1.00 MAPK1 (0.65) MAPK1LGALS8LGALS3LGALS4CETP
SCHEMBL22691938 1.00 MAPK1 (0.65) MAPK1LGALS8LGALS3LGALS4CETP
SCHEMBL22111992 1.00 MAPK1 (0.65) MAPK1LGALS8LGALS3LGALS4CETP
SCHEMBL21067398 1.00 MAPK1 (0.65) MAPK1LGALS8LGALS3LGALS4CETP
SCHEMBL2446731 1.00 MAPK1 (0.65) MAPK1LGALS8LGALS3LGALS4CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11433136-B2 Polyacetal polymers, conjugates, particles and uses thereof THE GENERAL HOSPITAL CORPORATION (US) 2022-09-06 US disclosed
WO-2020201771-A1 NEW PHARMACEUTICAL COMPOSITIONS OREXO AB (SE) 2020-10-08 WO disclosed
WO-2020201768-A1 PHARMACEUTICAL COMPOSITIONS OREXO AB (SE) 2020-10-08 WO disclosed
WO-2019064026-A1 NEW PHARMACEUTICAL COMPOSITIONS OREXO AB (SE) 2019-04-04 WO disclosed
US-20180360978-A1 POLYACETAL POLYMERS, CONJUGATES, PARTICLES AND USES THEREOF THE GENERAL HOSPITAL CORPORATION (US) 2018-12-20 US disclosed
EP-3389720-A1 POLYACETAL POLYMERS, CONJUGATES, PARTICLES AND USES THEREOF The General Hospital Corporation (US) 2018-10-24 EP disclosed
WO-2018106738-A1 BRUSH-ARM STAR POLYMERS, CONJUGATES AND PARTICLES, AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2018-06-14 WO disclosed
WO-2017106630-A1 POLYACETAL POLYMERS, CONJUGATES, PARTICLES AND USES THEREOF THE GENERAL HOSPITAL CORPORATION (US) 2017-06-22 WO disclosed
US-7566766-B2 Peptides which enhance transport across tissues and methods of identifying and using the same EUSA Pharma Ltd. (GB) 2009-07-28 US disclosed
US-20060275746-A9 Peptides which enhance transport across tissues and methods of identifying and using the same O'MAHONY DANIEL J 2006-12-07 US disclosed
US-6521737-B1 Coded by bacteriophage from selected library; drug delivery ELAN CORPORATION, PLC (IE) 2003-02-18 US disclosed
EP-1281718-A2 Peptides which enhance transport across tissues ELAN CORPORATION, Plc (IE) 2003-02-05 EP disclosed
US-6361938-B1 ADMINISTERING IN SITU OR IN VITRO A KNOWN AMOUNT OF PHAGE FROM A RANDOM PHAGE LIBRARY INTO THE GASTRO-INTESTINE TRACT OF AN ANIMAL; AFTER A TIME PERIOD, PHAGE TRANSPORTED ACROSS A TISSUE BARRIER IS HARVESTED FROM BLOOD OR BRAIN TISSUE ELAN CORPORATION, PLC (IR) 2002-03-26 US disclosed
US-6117632-A DETECTION OF PROTEIN SEQUENCES WHICH TRANSFER COMPOUNDS ACROSS HUMAN AND ANIMAL TISSUES; INCUBATION OF PHAGE WITH TISSUE, RECOVER TRANSPORTED PHAGE, AMPLIFY, REPEAT PROCESS WITH RECOVERED PHAGE, DETECT TRANSPORT PROTEIN SEQUENCES ELAN CORPORATION, PLC (IE) 2000-09-12 US disclosed
EP-0981649-A1 PEPTIDES WHICH ENHANCE TRANSPORT OF AN ACTIVE AGENT ACROSS TISSUES AND COMPOSITIONS AND METHODS OF USING THE SAME ELAN CORPORATION, Plc (IE) 2000-03-01 EP disclosed
WO-1998051825-A1 PEPTIDES WHICH ENHANCE TRANSPORT OF AN ACTIVE AGENT ACROSS TISSUES AND COMPOSITIONS AND METHODS OF USING THE SAME ELAN CORPORATION, PLC (IE) 1998-11-19 WO disclosed
EP-0876615-A1 PEPTIDES WHICH ENHANCE TRANSPORT ACROSS TISSUES AND METHODS OF IDENTIFYING AND USING THE SAME ELAN CORPORATION PLC (IE) 1998-11-11 EP disclosed
EP-0859959-A1 PEPTIDES WHICH ENHANCE TRANSPORT ACROSS TISSUES AND METHODS OF IDENTIFYING AND USING THE SAME ELAN CORPORATION, Plc (IE) 1998-08-26 EP disclosed
WO-1997017613-A1 PEPTIDES WHICH ENHANCE TRANSPORT ACROSS TISSUES AND METHODS OF IDENTIFYING AND USING THE SAME ELAN CORPORATION, PLC (IE) 1997-05-15 WO disclosed
WO-1997017614-A1 PEPTIDES WHICH ENHANCE TRANSPORT ACROSS TISSUES AND METHODS OF IDENTIFYING AND USING THE SAME ELAN CORPORATION, PLC (IE) 1997-05-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180360978-A1 POLYACETAL POLYMERS, CONJUGATES, PARTICLES AND USES THEREOF CD44, FUT6, MSN MAPK1 3621/4885LGALS8 347/4885LGALS3 128/4885
US-11433136-B2 Polyacetal polymers, conjugates, particles and uses thereof CD44, FUT6, MSN MAPK1 3621/4885LGALS8 347/4885LGALS3 128/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.