SCHEMBL4515920

SCHEMBL4515920

CCC(C)C(NC(=O)C(CCC(=O)O)NC(=O)C(N)CC(C)C)C(=O)NC(CC(N)=O)C(=O)NC(CCCNC(=N)N)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ ENPEP Q07075 5/20 0.48
▸ BACE1 P56817 5/20 0.47
▸ KISS1R Q969F8 2/20 0.45
▸ CTSD P07339 2/20 0.45
▸ VIPR2 P41587 3/20 0.43
▸ VIPR1 P32241 1/20 0.43
▸ MDM4 O15151 1/20 0.43
▸ MDM2 Q00987 1/20 0.43
▸ GRIN2D O15399 1/20 0.43
▸ GRIN3B O60391 1/20 0.43
▸ GRIN1 Q05586 1/20 0.43
▸ GRIN2A Q12879 1/20 0.43
▸ GRIN2B Q13224 1/20 0.43
▸ GRIN2C Q14957 1/20 0.43
▸ GRIN3A Q8TCU5 1/20 0.43
▸ NPY4R P50391 3/20 0.43
▸ NPY1R P25929 2/20 0.43
▸ NPY2R P49146 2/20 0.43
▸ NPY5R Q15761 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4515922 1.00 ENPEP (0.48) ENPEPBACE1KISS1RCTSDVIPR2
SCHEMBL30974368 0.92 ENPEP (0.48) ENPEPBACE1KISS1RVIPR2VIPR1
SCHEMBL31394924 0.92 ENPEP (0.55) ENPEPBACE1
SCHEMBL30739155 0.91 ENPEP (0.52) ENPEPBACE1VIPR2VIPR1
SCHEMBL30483972 0.90 ENPEP (0.49) ENPEPBACE1KISS1RVIPR2VIPR1
SCHEMBL31157662 0.90 ENPEP (0.52) ENPEPBACE1MDM4MDM2NPY4R
SCHEMBL31415951 0.90 NPY4R (0.46) ENPEPNPY4RNPY1RNPY2RNPY5R
SCHEMBL30512550 0.89 VIPR2 (0.48) ENPEPVIPR2VIPR1GRIN2DGRIN3B
SCHEMBL31299909 0.89 VIPR1 (0.48) BACE1KISS1RCTSDVIPR2VIPR1
SCHEMBL30879458 0.89 BACE1 (0.47) ENPEPBACE1VIPR2VIPR1NPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE50178-E1 Humanised antibodies UCB Biopharma SRL (BE) 2024-10-22 — — US disclosed
US-RE48787-E1 Humanised antibodies UCB Biopharma SRL (BE) 2021-10-26 — — US disclosed
US-7566771-B1 Humanised antibodies CELLTECH R&D LIMITED (GB) 2009-07-28 — — US disclosed
EP-0460167-A1 HUMANISED ANTIBODIES. CELLTECH LTD (GB) 1991-12-11 — — EP disclosed
WO-1991009967-A1 HUMANISED ANTIBODIES CELLTECH LIMITED (GB) 1991-07-11 — — WO disclosed
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