Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30720042 | 0.87 | TSHR (0.39) | CA4ALDH1A1LTA4HTSHRTRPA1 | |
| SCHEMBL27482970 | 0.79 | CA4 (0.41) | CA4LTA4HTSHRPPARGPPARA | |
| SCHEMBL947518 | 0.79 | CA4 (0.41) | CA4ALDH1A1LTA4HTSHRPPARG | |
| SCHEMBL28141131 | 0.79 | LTA4H (0.37) | CA4ALDH1A1LTA4HTSHRPPARG | |
| SCHEMBL4306370 | 0.74 | KDM4E (0.39) | CA4ALDH1A1LTA4HTSHRTRPA1 | |
| SCHEMBL509577 | 0.73 | TSHR (0.39) | CA4ALDH1A1LTA4HTSHRTRPA1 | |
| SCHEMBL3906412 | 0.70 | CA4 (0.50) | CA4LTA4HTSHRPPARGPPARA | |
| SCHEMBL2356964 | 0.70 | CA4 (0.50) | CA4ALDH1A1LTA4HTSHRKDM4E | |
| SCHEMBL3961288 | 0.70 | TSHR (0.37) | CA4ALDH1A1LTA4HTSHRTRPA1 | |
| SCHEMBL11388127 | 0.70 | TRPA1 (0.46) | CA4ALDH1A1LTA4HTSHRTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318481-A1 | Potentiators Of Glutamate Receptors | AICHER THOMAS DANIEL | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318481-A1 | Potentiators Of Glutamate Receptors | GRIK1, GRIK2, GRIK4 | CA4 2337/4885ALDH1A1 1737/4885LTA4H 1319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.