SCHEMBL4516244

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4517138	0.83	HSD11B1 (0.52)	ALDH1A1HSD11B1MEN1MAPTKMT2A
	SCHEMBL4500752	0.83	HSD11B1 (0.39)	HSD11B1HPGDSCN9ALIPE
	SCHEMBL4526922	0.82	HSD11B1 (0.47)	ALDH1A1HSD11B1FFAR1HPGDLIPE
	SCHEMBL4517793	0.81	HSD11B1 (0.52)	LMNAALDH1A1HSD11B1MEN1KMT2A
	SCHEMBL3002570	0.79	HSD11B1 (0.57)	ALDH1A1HSD11B1FFAR1
	SCHEMBL14365302	0.78	SCN9A (0.43)	SCN9ALIPE
	SCHEMBL4520465	0.78	HPGD (0.48)	HSD11B1FFAR1HPGDPOLB
	SCHEMBL4513450	0.77	HSD11B1 (0.48)	HSD11B1HPGD
	SCHEMBL4514536	0.77	SCN9A (0.47)	SCN9ALIPE
	SCHEMBL4519067	0.77	HSD11B1 (0.50)	HSD11B1FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.